Quantification of Human Plasma-Busulfan Concentration by Liquid Chromatography-Tandem Mass Spectrometry

机译：液相色谱-串联质谱法定量测定人血浆中的硫丹浓度

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BackgroundBusulfan, an alkylating agent administered prior to hematopoietic stem cell transplantation, has a narrow therapeutic range and wide variability in metabolism. We developed a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for rapid and accurate quantification of plasma busulfan.

机译：背景技术硫丹是在造血干细胞移植之前施用的烷化剂，具有狭窄的治疗范围和广泛的代谢变异性。我们开发了一种液相色谱-串联质谱（LC-MS / MS）方法，用于快速，准确地定量血浆白消安。

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期刊名称 Annals of Laboratory Medicine
作者
Soo Young Moon; Min Kyoo Lim; Susie Hong; Yongbum Jeon; Minje Han; Sang Hoon Song; Kyoung Soo Lim; Kyung-Sang Yu; In-Jin Jang; Ji Won Lee; Hyoung Jin Kang; Junghan Song;
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作者单位

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年(卷),期 2014(34),1
年度 2014
页码 7–14
总页数 8
原文格式 PDF
正文语种
中图分类情报学;
关键词
Busulfan Drug monitoring Tandem mass spectrometry Liquid chromatography Hematopoietic stem cell transplantation;

机译：白消安;药物监测;串联质谱;液相色谱;造血干细胞移植;

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专利

1. Quantification of Human Plasma-Busulfan Concentration by Liquid Chromatography-Tandem Mass Spectrometry [J] . Annals of laboratory medicine. . 2014,第1期

机译：液相色谱-串联质谱法定量测定人血浆中的硫丹浓度
2. Quantifications of saxitoxin concentrations in bivalves by high performance liquid chromatography-tandem mass spectrometry with the purification of immunoaffinity column [J] . Yue Yajun, Zhu Bo, Lun Lili, Journal of chromatography, B. Analytical technologies in the biomedical and life sciences . 2020,第期

机译：通过高效液相色谱 - 串联质谱法测定山豆蛋白浓度的脂肪毒素浓度与免疫亲和力柱的纯化
3. A candidate reference measurement procedure for quantifying serum concentrations of 25-hydroxyvitamin D-3 and 25-hydroxyvitamin D-2 using isotope-dilution liquid chromatography-tandem mass spectrometry [J] . Mineva Ekaterina M., Schleicher Rosemary L., Chaudhary-Webb Madhulika, Analytical and bioanalytical chemistry . 2015,第19期

机译：使用同位素稀释液相色谱-串联质谱法定量25-羟基维生素D-3和25-羟基维生素D-2血清浓度的候选参考测量程序
4. A HIGHLY SENSITIVE METHOD FOR THE QUANTIFICATION OF DEXMEDETOMIDINE IN HUMAN PLASMA BY LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY [C] . Min Chang Kim, Seo Hyun Yoon, Joo-Youn Cho ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：通过液相色谱 - 串联质谱法测量人血浆中右甲丁络胺的高敏感方法
5. Examination of Concentrations of THC and Its Major Metabolites in Postmortem Blood Using Solid-Phase Extraction Preparation Methods and Analysis by Liquid Chromatography-Tandem Mass Spectrometry [D] . Tully, Andrea Kristin 2018

机译：固相萃取制备方法检测死后血液中四氢大麻酚及其主要代谢物的浓度，并通过液相色谱-串联质谱法进行分析
6. A Candidate Reference Measurement Procedure for Quantifying Serum Concentrations of 25-Hydroxyvitamin D3 and 25-Hydroxyvitamin D2 Using Isotope-Dilution Liquid Chromatography-Tandem Mass Spectrometry [O] . Ekaterina M. Mineva, Rosemary L. Schleicher, Madhulika Chaudhary-Webb, -1

机译：使用同位素稀释液相色谱-串联质谱法定量25-羟基维生素D3和25-羟基维生素D2的血清浓度的候选参考测量程序
7. A candidate reference measurement procedure for quantifying serum concentrations of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 using isotope-dilution liquid chromatography-tandem mass spectrometry [O] . Ekaterina M. Mineva, Rosemary L. Schleicher, Madhulika Chaudhary-Webb, 2015

机译：使用同位素稀释液相色谱 - 串联质谱法定量25-羟基乙多素D3和25-羟基vitamind2的血清浓度的候选参考测量程序

Quantification of Human Plasma-Busulfan Concentration by Liquid Chromatography-Tandem Mass Spectrometry

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