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Management of gallstone disease in the elderly.

机译:老年人胆结石疾病的管理。

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摘要

AIM: To determine the outcome of management of symptomatic gallstone disease (GSD) in patients aged 80 years or more. PATIENTS AND METHODS: A retrospective review of the outcome of 79 patients admitted to 2 district general hospitals with symptomatic GSD over a 1-year period was undertaken. Patients were grouped according to method of management: non-operative, ERCP, and cholecystectomy. POSSUM scores for the ERCP and cholecystectomy groups were calculated and observed, and predicted outcome compared. RESULTS: Obstructive jaundice and biliary colic were the most common presenting symptoms. Each patient had been admitted at least once before the study period (median, 2; range, 1-3). Outcomes are detailed in Table 1. Non-operative management failed in 18 of 23 patients, with 17.4% mortality. ERCP was successful in 40 of 47 patients with 3 complications (0.24 of predicted) and no mortality. In all, 11 laparoscopic and 12 open cholecystectomies were performed with 6 complications and 1 mortality (0.95 and 0.83 of predicted, respectively): 4 complications and the only death occurring after emergency cholecystectomy. Table 1 Outcomes Management Number Mortality Morbidity Outcome Non-operative 23 4 9 5 OK, 13 re-admitted, 4 still symptomatic ERCP 47 0 3 1 PTC, 6 operated Operative 23 1 6 Conclusions: This study suggests that recurrent GSD in elderly patients managed non-operatively may have fatal outcome. Elective cholecystectomy has acceptable morbidity and mortality in this age group and there is often ample opportunity to avoid emergency surgery, but a prospective randomised study is required to improve clinical algorithms.
机译:目的:确定80岁或以上的症状性胆结石病(GSD)的治疗结果。病人和方法:回顾性回顾了两年内有症状GSD的两家地区综合医院收治的79例患者的结果。根据治疗方法对患者分组:非手术,ERCP和胆囊切除术。计算并观察ERCP组和胆囊切除术组的POSSUM评分,并比较预测结果。结果:梗阻性黄疸和胆绞痛是最常见的症状。在研究期之前,每名患者至少入院一次(中位数2;范围1-3)。结果详细列于表1。23例患者中有18例非手术治疗失败,死亡率为17.4%。 ERCP在47例患者中有40例成功,有3例并发症(预计为0.24例)且无死亡。总共进行了11例腹腔镜检查和12例开放性胆囊切除术,其中有6例并发症和1例死亡(分别为预测值的0.95和0.83):4例并发症,唯一的死亡发生在紧急胆囊切除术后。表1结果管理数死亡率死亡率非手术23 4 9 5好,13再次入院,4仍然有症状ERCP 47 0 3 1 PTC,6手术手术23 1 6结论:这项研究表明,老年患者的GSD复发可以控制非手术可能会导致致命的后果。择期胆囊切除术在这个年龄段的患者中具有可接受的发病率和死亡率,并且通常有充足的机会避免进行急诊手术,但是需要进行前瞻性随机研究以改善临床算法。

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