首页> 美国卫生研究院文献>Annals of The Royal College of Surgeons of England >Early post-splenectomy sepsis after missile injury in adults.
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Early post-splenectomy sepsis after missile injury in adults.

机译:成人导弹损伤后脾切除术后早期败血症。

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摘要

Early septic complications were studied in 292 patients operated on for penetrating missile injury of the abdomen with involvement of either the spleen or the liver, at Basrah Teaching Hospital between January 1983 and April 1986. Depending on associated injuries, patients with splenectomy were divided into three groups, the first with isolated splenic injury, the second with splenic and associated extra-intestinal organ injury, and the third with splenic and intestinal injuries with or without extra-intestinal organ injury. Patients with hepatic injury were classified similarly. Splenectomy was carried out for any degree of splenic injury. Grade I hepatic injuries were managed by débridement and suturing while major grades II-IV underwent segmentectomy or lobectomy. Patients were considered septic if they had any three of four clinical criteria: temperature higher than 39 degrees C; significant haemodynamic deterioration; respiratory alkalosis, or oliguria. Of the total, 79 were excluded due to: early transfer 51, incomplete records 8, perioperative death 11, and having combined splenic and hepatic injuries 9 (excluded by definition), leaving 104 (74.8%) patients with splenectomy and 109 (71.1%) with hepatic injury available for study. Sepsis developed in 48 (46.1%) of patients after splenectomy and in 28 (25.7%) with hepatic injury. This difference was significant (P greater than 0.005). In patients with isolated splenic injury, eight (25.8%) were septic while three (13.6%) of those with isolated hepatic injury developed sepsis. This was not significant (P = 0.32, Fisher's exact test). When either was associated with an injury to an extra-intestinal organ, 15 (50%) of the splenectomy group developed sepsis compared to five (23.8%) of the hepatic injury group.(ABSTRACT TRUNCATED AT 250 WORDS)
机译:在1983年1月至1986年4月间,在巴士拉教学医院对292例因脾脏或肝脏受累的腹部穿透性导弹损伤进行手术的早期脓毒症并发症进行了研究。根据相关损伤,将脾切除患者分为三类两组,第一组为单纯性脾损伤,第二组为脾和相关肠外器官损伤,第三组为脾和肠损伤,有或无肠外器官损伤。肝损伤患者的分类相似。对任何程度的脾损伤行脾切除术。 I级肝损伤通过清创术和缝合进行处理,而II-IV级主要肝切除术或肺叶切除术。如果患者具有以下四个临床标准中的任何三个,则被认为是败血症:温度高于39摄氏度;血液动力学显着恶化;呼吸性碱中毒或尿少。在总数中,有79例因以下原因而被排除在外:早期转移51,不完整记录8,围手术期死亡11,合并脾脏和肝损伤9(按定义排除),剩下104例(74.8%)进行脾切除术和109例(71.1%) )有肝损伤可供研究。脾切除术后48例(46.1%)患者发生败血症,28例肝损伤(25.7%)患者发生脓毒症。该差异是显着的(P大于0.005)。在单纯性脾损伤患者中,有8名(25.8%)败血症,而单纯性肝损伤中的3名(13.6%)发展为败血症。这并不显着(P = 0.32,Fisher精确检验)。当任何一个都与肠外器官损伤相关时,脾切除术组中有15个(50%)发生败血症,而肝损伤组中有五个(23.8%)发生了败血症(摘要截断为250个单词)

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