Ninety-eight hepatic resections for hepatocellular carcinoma were performed on 94 patients from 1963-1985. HBs antigen was positive in 17% of patients, preoperative serum alpha-fetoprotein was more than 20 ng/mL in 70% of patients, and liver cirrhosis was present in 75% of patients. Hospital mortality rate was 19%, and the volume of operative blood loss was the most decisive factor that affected the short-term prognosis. Excluding the 19 hospital deaths, the long-term survival rates of 75 patients were 73%, 42%, and 25% for 1, 3, and 5 years, respectively. Prognostic factors that influenced the long-term prognosis were investigated by comparing the survival curves. Significant differences of survival patterns were noted when analyzed on the basis of preoperative alpha-fetoprotein level (less than or equal to 200 vs. greater than 200 ng/mL), tumor size (less than or equal to 5 vs. greater than 5 cm), and tumor capsule. The recurrence of carcinoma was the main cause of death in 56% (42 patients) who died after discharge from the hospital. The development of effective prevention and treatment against recurrent tumors is necessary to improve long-term prognosis.
展开▼
机译：从1963年至1985年，对94例肝癌进行了98例肝切除。 HBs抗原阳性的患者为17％，术前血清甲胎蛋白超过20 ng / mL的患者为70％，肝硬化的患者为75％。医院死亡率为19％，手术失血量是影响短期预后的最决定性因素。不包括19例医院死亡，75名患者在1年，3年和5年的长期存活率分别为73％，42％和25％。通过比较生存曲线，研究了影响长期预后的预后因素。根据术前α-甲胎蛋白水平（小于或等于200 ngs。大于200 ng / mL），肿瘤大小（小于或等于5 vs.大于5 cm）进行分析时，发现生存模式存在显着差异。 ）和肿瘤包膜。癌症复发是导致出院后死亡的56％（42例患者）的主要死亡原因。有效的预防和治疗复发性肿瘤对于改善长期预后是必要的。
展开▼
