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Acute Traumatic Thoracic Aortic Injury: Considerations and Reflections on the Endovascular Aneurysm Repair

机译:急性创伤性胸主动脉损伤:血管内动脉瘤修复的考虑和思考

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摘要

Traumatic rupture of the thoracic aorta is a life-threatening lesion and it occurs in 10 to 30% of fatalities from blunt thoracic trauma and is the second most common cause of death after head injury. Immediate surgery is often characterized by a high mortality and morbidity rate. Delayed repair of traumatic aortic injuries has significant survival benefits and a much lower mortality rate compared with early open repair. Despite developments in operative techniques, there still remains considerable operative mortality and morbidity associated with a surgical approach even if delayed. Endovascular stent grafts for the thoracic aorta represents an alternative to the conventional approach for traumatic aortic rupture. Because of the lower invasivity avoiding thoracotomy and use of heparin, endovascular repair can be applied in acute patients without the risk of destabilizing pulmonary, head or abdominal traumatic lesions. However, despite the good deal of convincing evidence for endovascular treatment for thoracic aortic diseases and for traumatic aortic injuries as a valid and efficacious alternative to surgery, several reports show a variety of late complications of thoracic endografts especially for first-generation stent-grafts. In light of this, is the endovascular treatment really safe, efficacious and free from complications in the long term? This manuscript aims to offer a moment of reflection on this important chapter of aortic pathology.
机译:胸主动脉外伤性破裂是危及生命的病变,在钝性胸外伤致死率中占10%至30%,是颅脑损伤后第二大最常见的死亡原因。立即手术通常以高死亡率和高发病率为特征。与早期开放式修复相比,创伤性主动脉损伤的延迟修复具有明显的生存优势,并且死亡率低得多。尽管手术技术有所发展,但即使手术延迟,仍与手术方法相关的手术死亡率和发病率仍然很高。用于胸主动脉的血管内支架移植物是创伤性主动脉破裂的传统方法的替代方法。由于避免开胸手术和使用肝素的低侵入性,血管内修复可用于急性患者,而不会破坏肺部,头部或腹部外伤的稳定性。然而,尽管有大量令人信服的证据证明胸腔主动脉疾病的血管内治疗和创伤性主动脉损伤是手术的有效替代方法,但仍有一些报告显示胸腔内移植物的各种晚期并发症,尤其是第一代支架移植物。有鉴于此,从长期来看,腔内治疗是否真的安全,有效且无并发症?该手稿旨在对这一重要的主动脉病理学章节进行反思。

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