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Osteochondral Allograft Transplantation of the Medial Femoral Condyle With Orthobiologic Augmentation and Graft-Recipient Microfracture Preparation

机译:骨bi突同种异体骨软骨移植同种异体骨移植及接骨接受者微骨折制备

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摘要

Osteochondritis dissecans (OCD) has been recognized for over 100 years yet still poses treatment challenges owing to both the avascular nature of articular cartilage and the inability to generate hyaline cartilage. The knee is most commonly involved, and without repair, patients have chronic knee pain, loose bodies, and early-onset osteoarthritis. There are a number of surgical techniques for repairing OCD, some of which are still being refined. Currently, common procedures used to treat OCD lesions include microfracture, autologous chondrocyte implantation, osteochondral autograft transplantation, and osteochondral allograft transplantation. In this Technical Note, we describe osteochondral allograft transplantation with the addition of platelet-rich plasma and graft-recipient microfracture. We believe the micropores augment the osteoconductive and osteoinductive properties of the allograft and aid in the incorporation of the allograft plug by improving angiogenesis, enhancing clot formation in the allograft, and providing a homogeneous environment for remodeling.
机译:解剖性骨软骨炎(OCD)已有100多年的历史了,但由于关节软骨的无血管性质和无法生成透明软骨,仍然给治疗带来挑战。膝关节受累最常见,且未经修复,患者会出现慢性膝关节疼痛,身体松弛和早发性骨关节炎。有许多用于修复强迫症的外科手术技术,其中一些仍在完善中。当前,用于治疗OCD损伤的常见程序包括微骨折,自体软骨细胞植入,自体软骨软骨移植和同种异体软骨移植。在本技术说明中,我们描述了同种异体骨软骨移植,以及富含血小板的血浆和移植受体微骨折。我们相信微孔增强了同种异体移植物的骨传导性和骨诱导性,并通过改善血管生成,增强同种异体移植物中的血凝块形成并提供均一的重塑环境来协助异种移植物栓塞的结合。

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