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No Evaluation of Serum P53 Levels in Iraqi Female Breast Cancer Patients

机译:没有评估伊拉克女性乳腺癌患者的血清P53水平

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摘要

Breast cancer is the most common cancer diagnosed and the second leading cause of cancer death among Iraqi women. The population was exposed to high levels of depleted uranium following the first and second Gulf Wars and this might be a risk factor. Protein 53 (p53) or Tumor protein 53 (Tp53) was originally defined as an oncogenic protein. The aim of the study was to evaluate P-53 serum concentrations in fifty Iraqi female breast cancer patients and twenty five healthy volunteers using the ELISA technique. All these patients attended the Teaching Hospital of AL Diwaniyah during the period between June 2016 to March 2017. The mean values for TP53 concentration in patients with breast cancer and apparently healthy groups were 47+33.5 U/ml and 27. 8+12.7 U/ml, respectively. The results showed no significantly difference, in contrast to most studies conducted elsewhere in the world.
机译:乳腺癌是被诊断为伊拉克妇女中最常见的癌症,也是癌症死亡的第二大主要原因。在第一次和第二次海湾战争之后,该人群暴露于大量贫化铀,这可能是一个危险因素。蛋白53(p53)或肿瘤蛋白53(Tp53)最初被定义为致癌蛋白。该研究的目的是使用ELISA技术评估50名伊拉克女性乳腺癌患者和25名健康志愿者中的P-53血清浓度。所有这些患者在2016年6月至2017年3月期间到AL Diwaniyah的教学医院就诊。乳腺癌患者和显然健康的人群中TP53浓度的平均值分别为47 + 33.5 U / ml和27. 8 + 12.7 U /毫升。与世界上其他地方进行的大多数研究相比,结果没有显着差异。

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