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Effects of Donepezil Hydrochloride on Neuronal Response of Pyramidal Neurons of the CA1 Hippocampus in Rat Model of Alzheimer’s Disease

机译：盐酸多奈哌齐对阿尔茨海默病大鼠模型海马CA1锥体神经元神经元反应的影响

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摘要

Introduction:Donepezil (DON), an Acetylcholinesterase Inhibitor (AChEI), is widely used in the treatment of Alzheimer’s Disease (AD). The current study aimed at evaluating the effect of donepezil hydrochloride on pyramidal neuron response in CA1 region of a rat model of AD.

机译：简介：乙酰胆碱酯酶抑制剂（AChEI）多奈哌齐（DON）被广泛用于治疗阿尔茨海默氏病（AD）。目前的研究旨在评估盐酸多奈哌齐对AD模型大鼠CA1区锥体神经元反应的影响。

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期刊名称 Basic and Clinical Neuroscience
作者
Azade Eskandary; Ahmad Ali Moazedi; Hosein Najaph Zade; Mohamad Reza Akhond;
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作者单位

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年(卷),期 2019(10),2
年度 2019
页码 109–117
总页数 10
原文格式 PDF
正文语种
中图分类神经科学;
关键词
Alzheimer’s Disease Electrophysiology Donepezil Rats;

机译：阿尔茨海默氏病;电生理学;多奈哌齐;大鼠;

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专利

1. Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: Correlation with cognitive performance and neuropathology in mild cognitive impairment and Alzheimer's disease [J] . Ginsberg Stephen D., Malek‐Ahmadi Michael H., Alldred Melissa J., Hippocampus . 2019,第5期

机译：CA1金字塔神经元和海马文学素和神经营养素受体基因的选择性下降：轻度认知障碍和阿尔茨海默病中的认知性能和神经病理学相关性
2. Electrophysiological responses in vivo of hippocampal CA1 pyramidal neurons in an animal model of neuronal migration disorders. [J] . Smith BN, Choi BJ, Roper SN, Developmental Neuroscience . 1999,第3a5期

机译：在神经元迁移障碍的动物模型中，海马CA1锥体神经元在体内的电生理反应。
3. Electrophysiological responses in vivo of hippocampal CA1 pyramidal neurons in an animal model of neuronal migration disorders. [J] . Smith BN, Choi BJ, Roper SN, Developmental Neuroscience . 1999,第3a5期

机译：在神经元迁移障碍的动物模型中，海马CA1锥体神经元在体内的电生理反应。
4. Mathematical Modelling of Magnesium Block-Driven NMDA Receptor Response in CA1 Pyramidal Neuron for Alzheimer's Disease [C] . Vijay Dave, Arpit D. Shrimankar, Devanshi Gokani, International Conference on Nanoelectronics Circuits Communication System . 2019

机译：Alzheimer疾病Ca1金字塔神经元中镁阻断NMDA受体反应的数学建模
5. Intrinsic plasticity in CA1 pyramidal neurons: Role of calcium(2+)- and sodium(+)-activated potassium currents in aging and Alzheimer's disease. [D] . Kaczorowski, Catherine Cook. 2006

机译：CA1锥体神经元的内在可塑性：钙（2+）和钠（+）激活的钾电流在衰老和阿尔茨海默氏病中的作用。
6. Analysis of Age-Dependent Alterations in Excitability Properties of CA1 Pyramidal Neurons in an APPPS1 Model of Alzheimer’s Disease [O] . Paola Vitale, Ana Rita Salgueiro-Pereira, Carmen Alina Lupascu, 2021

机译：Alzheimer疾病APPPS1模型Ca1金字塔神经元兴奋性特性的年龄依赖性变化分析
7. Effects of Donepezil Hydrochloride on Neuronal Response of Pyramidal Neuron of the CA1 Hippocampus in Rat Model of Alzheimer's Disease [O] . Azade Eskandary, Ahmad ali Moazedi, Hossein Nejafzade, 2018

机译：盐酸多奈哌齐林素对阿尔茨海默病大鼠大鼠模型Ca1海马金字塔神经元神经元响应的影响
8. Effects of Dithiothreitol, a Sulfhydryl Reducing Agent, on CA1 Pyramidal Cells of the Guinea Pig Hippocampus In vitro [R] . Tolliver, J. M., Pellmar, T. C. 1988

机译：巯基还原剂二硫苏糖醇对豚鼠海马Ca1区锥体细胞的影响

Effects of Donepezil Hydrochloride on Neuronal Response of Pyramidal Neurons of the CA1 Hippocampus in Rat Model of Alzheimer’s Disease

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