Comparison of Amikacin Pharmacokinetics in Neonates Following Implementation of a New Dosage Protocol

摘要

OBJECTIVESThe primary aim was to compare attainment of goal serum amikacin concentrations using two dosage regimens in patients admitted to a neonatal intensive care unit. Secondary objectives included comparison of percentages of supratherapeutic trough concentrations, and subtherapeutic and supratherapeutic peak concentrations.