Behavioral phenotype in five individuals with de novo mutations within the GRIN2B gene

摘要

BackgroundIntellectual disability (ID) is often associated with behavioral problems or disorders. Mutations in the GRIN2B gene (MRD6, MIM613970) have been identified as a common cause of ID (prevalence of 0.5 – 1% in individuals with ID) associated with EEG and behavioral problems.