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Automatic detection of bioresorbable vascular scaffold struts in intravascular optical coherence tomography pullback runs

机译:在血管内光学相干断层扫描回撤运行中自动检测可生物吸收的血管支架撑杆

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摘要

Bioresorbable vascular scaffolds (BVS) have gained significant interest in both the technical and clinical communities as a possible alternative to metallic stents. For accurate BVS analysis, intravascular optical coherence tomography (IVOCT) is currently the most suitable imaging technique due to its high resolution and the translucency of polymeric BVS struts for near infrared light. However, given the large number of struts in an IVOCT pullback run, quantitative analysis is only feasible when struts are detected automatically. In this paper, we present an automated method to detect and measure BVS struts based on their black cores in IVOCT images. Validated using 3 baseline and 3 follow-up data sets, the method detected 93.7% of 4691 BVS struts correctly with 1.8% false positives. In total, the Dice’s coefficient for BVS strut areas was 0.84. It concludes that this method can detect BVS struts accurately and robustly for tissue coverage measurement, malapposition detection, strut distribution analysis or 3D scaffold reconstruction.
机译:作为金属支架的可能替代品,生物可吸收血管支架(BVS)在技术和临床领域都引起了广泛兴趣。对于精确的BVS分析,血管内光学相干断层扫描(IVOCT)由于其高分辨率和聚合物BVS支杆对近红外光的半透明性,目前是最适合的成像技术。但是,考虑到IVOCT撤回运行中的支撑杆数量众多,仅当自动检测到支撑杆时,定量分析才是可行的。在本文中,我们提出了一种基于IVOCT图像中BVS支杆黑芯的自动检测和测量方法。使用3个基线和3个随访数据集进行了验证,该方法正确检测了4691个BVS支杆的93.7%,假阳性率为1.8%。总体来说,BVS支杆区域的骰子系数为0.84。结论表明,该方法可以准确,可靠地检测BVS支杆,以进行组织覆盖率测量,错位检测,支杆分布分析或3D支架重建。

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