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Mathematical approach to unpinning of spiral waves anchored to an obstacle with high-frequency pacing

机译:用高频起搏解开锚定在障碍物上的螺旋波的数学方法

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摘要

Spiral waves are observed in wide variety of reaction-diffusion systems. Those observed in cardiac tissues are important since they are related to serious disease that threatens human lives, such as atrial or ventricular fibrillation. We consider the unpinning of spiral waves anchored to a circular obstacle on excitable media using high-frequency pacing. Here, we consider two types of the obstacle; i.e., that without any diffusive interaction with the environment, and that with diffusive interaction. We found that the threshold frequency for success in unpinning is lower for the obstacle with diffusive interaction than for the one without it. We discuss the threshold frequency based on the angular velocity of a chemical wave anchoring the obstacle.
机译:在各种各样的反应扩散系统中都观察到了螺旋波。在心脏组织中观察到的那些非常重要,因为它们与威胁人类生命的严重疾病(如心房或心室纤颤)有关。我们考虑使用高频起搏将锚定在可激励介质上的圆形障碍物上的螺旋波解开。在这里,我们考虑两种类型的障碍;即与环境之间没有任何扩散相互作用,以及与环境之间没有扩散相互作用。我们发现,具有扩散相互作用的障碍物的成功解除固定的阈值频率低于没有扩散相互作用的障碍物。我们基于锚定障碍物的化学波的角速度讨论阈值频率。

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