A general modeling and visualization tool for comparing different members of a group: application to studying tau-mediated regulation of microtubule dynamics

摘要

BackgroundInnumerable biological investigations require comparing collections of molecules, cells or organisms to one another with respect to one or more of their properties. Almost all of these comparisons are performed manually, which can be susceptible to inadvertent bias as well as miss subtle effects. The development and application of computer-assisted analytical and interpretive tools could help address these issues and thereby dramatically improve these investigations.