Human Papillomavirus-associated oropharyngeal cancer: an observational study of diagnosis prevalence and prognosis in a UK population

摘要

BackgroundThe incidence of Human Papillomavirus (HPV) associated oropharyngeal cancer (OPC) is increasing. HPV-associated OPC appear to have better prognosis than HPV-negative OPC. The aim of this study was to robustly determine the prevalence of HPV-positive OPC in an unselected UK population and correlate HPV positivity with clinical outcome.