Synthesis characterization X-ray structure computational studies and bioassay of novel compounds combining thiophene and benzimidazole or 124-triazole moieties

摘要

BackgroundDue to their interesting and versatile biological activity, thiophene-containing compounds have attracted the attention of both chemists and medicinal chemists. Some of these compounds have anticancer, antibacterial, antiviral, and antioxidant activity. In addition, the thiophene nucleus has been used in the synthesis of a variety of heterocyclic compounds.