[Purpose] To investigate the predictive value of maximum inspiratory pressure (MIP) and the rapid shallow breathing index (RSBI) in a ventilator weaning protocol and to evaluate the differences between clinical and surgical patients in the intensive care unit. [Subjects and Methods] Patients aged ≥15 years who underwent orotracheal intubation for mechanical ventilation and who met the criteria of the weaning protocol were included in the study. Receiver operating characteristic (ROC) curves were calculated for the analysis of each index. [Results] Logistic regression analysis was also performed. MIP showed greater sensitivity and specificity [area under the curve (AUC): 0.95 vs. 0.89] and likelihood ratios (LR) (positive(+): 20.85 vs. 9.45; negative(−): 0.07 vs. 0.17) than RSBI in the overall sample (OS) as well as in clinical patients (CP) (AUC: 0.99 vs. 0.90; LR+: 24.66 vs. 7.22; LR-: 0.01 vs. 0.15) and surgical patients (SP) (AUC: 0.99 vs. 0.87; LR+: 9.33 vs. 5.86; LR−: 0.07 vs. 0.14). The logistic regression analysis revealed that both parameters were significantly associated with the weaning success. The MIP showed greater accuracy than the RSBI (OS: 0.93 vs. 0.85; CP: 0.98 vs. 0.87; SP: 0.93 vs. 0.87). [Conclusion] Both parameters are good predictors of successful ventilator weaning.
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机译：［目的］研究呼吸机断奶方案中最大吸气压力（MIP）和快速浅呼吸指数（RSBI）的预测值，并评估重症监护室中临床和手术患者之间的差异。 [对象和方法]≥15岁的患者经口气管插管进行机械通气并且符合断奶方案的标准。计算接收器工作特性（ROC）曲线以分析每个指标。 [结果]还进行了逻辑回归分析。 MIP显示出比RSBI更高的敏感性和特异性[曲线下面积（AUC）：0.95对0.89]和似然比（LR）（正（+）：20.85对9.45；负（-）：0.07对0.17）。总样本（OS）以及临床患者（CP）（AUC：0.99 vs.0.90; LR +：24.66 vs. 7.22; LR-：0.01 vs.0.15）和手术患者（SP）（AUC：0.99 vs. 0.87； LR +：9.33与5.86； LR-：0.07与0.14）。 Logistic回归分析显示，这两个参数均与断奶成功率显着相关。 MIP显示出比RSBI更高的准确性（OS：0.93对0.85； CP：0.98对0.87； SP：0.93对0.87）。 ［结论］这两个参数都是成功的呼吸机断奶的良好预测指标。
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