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Inhibition of chemokine expression in rat inflamed paws by systemic use of the antihyperalgesic oxidized ATP

机译：全身使用抗痛觉过敏的氧化ATP抑制大鼠发炎的趋化因子表达

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BackgroundWe previously showed that local use of periodate oxidized ATP (oATP, a selective inhibitor of P2X7 receptors for ATP) in rat paw treated with Freund's adjuvant induced a significant reduction of hyperalgesia Herein we investigate the role of oATP, in the rat paws inflamed by carrageenan, which mimics acute inflammation in humans.

机译：背景我们以前表明，在用弗氏佐剂治疗的大鼠爪中局部使用高碘酸盐氧化的ATP（oATP，ATP的P2X7受体选择性抑制剂）可明显减轻痛觉过敏。本文研究了oATP在角叉菜胶引起的大鼠爪中的作用。模仿人类的急性炎症。

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期刊名称 BMC Immunology
作者
Alessandro Fulgenzi; Giacomo DellAntonio; Chiara Foglieni; Elena Dal Cin; Paolo Ticozzi; Josè S Franzone; Maria Elena Ferrero;
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作者单位

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年(卷),期 2005(6),-1
年度 2005
页码 18
总页数 11
原文格式 PDF
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中图分类免疫学;
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专利

1. Inhibition of chemokine expression in rat inflamed paws by systemic use of the antihyperalgesic oxidized ATP [J] . Alessandro Fulgenzi, Giacomo DellAntonio, Chiara Foglieni, BMC Immunology . 2005,第1期

机译：全身使用抗痛觉过敏的氧化ATP抑制大鼠发炎的趋化因子表达
2. Regulation of Cytokine Polarization and T Cell Recruitment to Inflamed Paws in Mouse Collagen-Induced Arthritis by the Chemokine Receptor CXCR6 [J] . Slauenwhite Drew, Gebremeskel Simon, Doucette Carolyn D., Arthritis & rheumatology. . 2014,第11期

机译：趋化因子受体CXCR6调节小鼠胶原诱导的关节炎中炎症因子的细胞因子极化和T细胞募集。
3. The importance of brain PGE2 inhibition versus paw PGE2 inhibition as a mechanism for the separation of analgesic and antipyretic effects of lornoxicam in rats with paw inflammation. [J] . Futaki N, Harada M, Sugimoto M, Journal of Pharmacy and Pharmacology . 2009,第5期

机译：脑PGE2抑制与爪子PGE2抑制作为氯诺昔康对大鼠发炎的镇痛和解热作用分离的机制的重要性。
4. Inhibition of TTX-r Na~+ Currents in Rat Sensory Neurons by NW-1029, a New Antihyperalgesic Agent [C] . Laura Faravelli, Ruggero G. Fariello, Patricia Salvati World Congress on Pain . 2003

机译：NW-1029，抑制大鼠感觉神经元的TTX-R Na +电流，NW-1029，一种新的抗神经剂
5. Mechanisms of Helicobacter pylori-induced inhibition of gastric H,K-ATPase expression. [D] . Saha, Arindam. 2009

机译：幽门螺杆菌诱导的抑制胃H，K-ATPase表达的机制。
6. Specific accumulation of technetium-99m radiolabelled negative liposomes in the inflamed paws of rats with adjuvant induced arthritis: effect of liposome size. [O] . W G Love, N Amos, I W Kellaway, 1989

机译：with诱导的关节炎大鼠发炎的爪中99m放射性标记的阴性脂质体的特异性积累：脂质体大小的影响。
7. Inhibition of chemokine expression in rat inflamed paws by systemic use of the antihyperalgesic oxidized ATP [O] . Ticozzi Paolo, Cin Elena, Foglieni Chiara, 2005

机译：全身使用抗痛觉过敏的氧化ATP抑制大鼠发炎的趋化因子表达
8. Increased Expression of the Chemokines CXCL1 and MIP-1a by Resident Brain Cells Precedes Neutrophil Infiltration in the Brain Following Prolonged Soman-Induced Status Epilepticus in Rats [R] . Johnson, E. A., Dao, T. L., Guignet, M. A., 2011

机译：驻留脑细胞增加趋化因子CXCL1和mIp-1a的表达在大鼠中长期梭曼诱导的癫痫持续状态后中性粒细胞浸润

Inhibition of chemokine expression in rat inflamed paws by systemic use of the antihyperalgesic oxidized ATP

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