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The estrogen receptor 1 gene affects bone mineral density and osteoporosis treatment efficiency in Slovak postmenopausal women

机译：雌激素受体1基因影响斯洛伐克绝经后妇女的骨矿物质密度和骨质疏松症的治疗效率

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摘要

BackgroundThe study investigated the associations of rs9340799:A > G (XbaI) and rs2234693:T > C (PvuII) polymorphisms in the estrogen receptor 1 gene (ESR1) with femoral neck (BMD-FN) and lumbar spine bone mineral density (BMD-LS), biochemical markers of bone turnover, calcium and phosphate levels, fracture prevalence, and a response to two types of anti-osteoporotic therapy in postmenopausal women from southern Slovakia.

机译：背景研究研究了雌激素受体1基因（ESR1）中rs9340799：A> G（XbaI）和rs2234693：T> C（PvuII）多态性与股骨颈（BMD-FN）和腰椎骨矿物质密度（BMD- LS），斯洛伐克南部绝经后妇女的骨代谢，钙和磷酸盐水平，骨折患病率以及对两种抗骨质疏松疗法的反应的生化指标。

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期刊名称 BMC Medical Genetics
作者
Vladimira Mondockova; Maria Adamkovicova; Martina Lukacova; Birgit Grosskopf; Ramona Babosova; Drahomir Galbavy; Monika Martiniakova; Radoslav Omelka;
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作者单位

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年(卷),期 2018(19),-1
年度 2018
页码 174
总页数 13
原文格式 PDF
正文语种
中图分类遗传学;
关键词
Osteoporosis ESR1 gene Polymorphisms BMD Fractures HT Estradiol Raloxifene;

机译：骨质疏松症;ESR1基因;多态性;BMD;骨折;HT;雌二醇;雷洛昔芬;

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专利

1. The estrogen receptor 1 gene affects bone mineral density and osteoporosis treatment efficiency in Slovak postmenopausal women [J] . Vladimira Mondockova, Maria Adamkovicova, Martina Lukacova, BMC Medical Genetics . 2018,第1期

机译：雌激素受体1基因影响斯洛伐克绝经后妇女的骨矿物质密度和骨质疏松症的治疗效率
2. A specific haplotype in the 3' end of estrogen-receptor alpha gene is associated with low bone mineral density in premenopausal women and increased risk of postmenopausal osteoporosis. [J] . Ongphiphadhanakul B, Chanprasertyothin S, Saetung S, Osteoporosis international: a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA . 2005,第10期

机译：雌激素受体α基因3'末端的特定单倍型与绝经前妇女的骨矿物质密度低和绝经后骨质疏松症的风险增加有关。
3. Relation of the estrogen receptor alpha gene microsatellite polymorphism to bone mineral density and the susceptibility to osteoporosis in postmenopausal Chinese women in Taiwan. [J] . Chen HY, Chen WC, Tsai HD, Maturitas: International Journal for the Study of the Climacteric . 2001,第2期

机译：台湾绝经后中国女性中雌激素受体α基因微卫星多态性与骨矿物质密度和骨质疏松症易感性的关系。
4. Relationship Between Bone Mineral Density and Polymorphism of the Estrogen Receptor Gene in Chinese Health Postmenopausal Women [C] . Huang qiren, Wang qinhong, Zhang liangpin, International congress on osteoporosis . 1999

机译：中国健康绝经后雌性雌激素受体基因骨密度与多态性的关系
5. Variability of bone mineral density in elderly postmenopausal women: Biochemical and genetic factors [D] . Scariano, John Kevin 2002

机译：绝经后老年妇女骨矿物质密度的变化：生化和遗传因素
6. Association of Vitamin D Receptor (FokI and BsmI) Gene Polymorphism with Bone Mineral Density and Their Effect on 25-Hydroxyvitamin D Level in North Indian Postmenopausal Women with Osteoporosis [O] . Israr Ahmad, Tabrez Jafar, Farzana Mahdi, 2018

机译：维生素D受体（FokI和BsmI）基因多态性与骨矿物质密度及其对北印度绝经后骨质疏松症妇女25-羟维生素D水平的影响
7. The Influence of Vitamin D Receptor Genetic Variants on Bone Mineral Density and Osteoporosis in Chinese Postmenopausal Women [O] . Wei He, Ming Liu, Xiaonan Huang, 2015

机译：维生素D受体遗传变异对中国绝经后妇女骨密度和骨质疏松症的影响

The estrogen receptor 1 gene affects bone mineral density and osteoporosis treatment efficiency in Slovak postmenopausal women

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