Genomic actions of 125-dihydroxyvitamin D3 on insulin receptor gene expression insulin receptor number and insulin activity in the kidney liver and adipose tissue of streptozotocin-induced diabetic rats

摘要

Backgroundthis study set out to examine the effects of the treatment with 1,25-dihydroxyvitamin D3 (1,25D3) [150 IU/Kg (3.75 μg/Kg) one a day, for 15 days] to non-diabetic rats and in rats rendered diabetic by a single injection of streptozotocin [65 mg/kg].