Efficacy of the epidural blood patch for the treatment of post lumbar puncture headache BLOPP: A randomised observer-blind controlled clinical trial ISRCTN 71598245

摘要

BackgroundPost dural punction headache (PDPH) occurs in 10% to 40% of the patients who had a lumbar puncture. Its symptoms can be severe and incapacitating. The epidural blood patch is widely accepted as the treatment of choice for postdural puncture headache. Uncontrolled studies report rapid recovery after patching in 90% to 100% of treated patients. However, sufficient evidence from randomised, controlled clinical trials is lacking.