Xanthine oxidoreductase mediates membrane docking of milk‐fat droplets but is not essential for apocrine lipid secretion

摘要

Key points class="unordered" style="list-style-type:disc" id="tjp7396-list-0001">Xanthine oxidoreductase (XOR) modulates milk lipid secretion and lactation initiation.XOR is required for butyrophilin1a1 clustering in the membrane during milk lipid secretion.XOR mediates apical membrane reorganization during milk lipid secretion.Loss of XOR delays milk fat globule secretion.XOR loss alters the proteome of milk fat globules.