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PD-L1 FGFR1 PIK3CA PTEN and p16 expression in pulmonary emphysema and chronic obstructive pulmonary disease with resected lung squamous cell carcinoma

机译：PD-L1FGFR1PIK3CAPTEN和p16在肺气肿和慢性阻塞性肺疾病合并肺鳞癌中的表达

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摘要

BackgroundEmphysema and chronic obstructive pulmonary disease (COPD) are well known independent risk factors for lung cancer. However, the developmental mechanisms between emphysema/COPD and lung cancer remain unknown. The purpose of this study was to evaluate PD-L1, FGFR1, PIK3CA, PTEN, and p16 expression in squamous cell carcinoma (SCC) associated with emphysema/COPD.

机译：背景肺气肿和慢性阻塞性肺疾病（COPD）是众所周知的肺癌独立危险因素。然而，肺气肿/ COPD与肺癌之间的发育机制仍然未知。这项研究的目的是评估与肺气肿/ COPD相关的鳞状细胞癌（SCC）中的PD-L1，FGFR1，PIK3CA，PTEN和p16表达。

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期刊名称 BMC Pulmonary Medicine
作者
Ken Arimura; Yasuo Sekine; Kenzo Hiroshima; Satoru Shimizu; Noriyuki Shibata; Mitsuko Kondo; Kiyoshi Takeyama; Etsuko Tagaya;
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作者单位

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年(卷),期 2019(19),-1
年度 2019
页码 169
总页数 7
原文格式 PDF
正文语种
中图分类外科学;
关键词
PD-L1 Lung squamous cell carcinoma Emphysema COPD;

机译：PD-L1;肺鳞状细胞癌;肺气肿;COPD;

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专利

1. PD-L1, FGFR1, PIK3CA, PTEN, and p16 expression in pulmonary emphysema and chronic obstructive pulmonary disease with resected lung squamous cell carcinoma [J] . Ken Arimura, Yasuo Sekine, Kenzo Hiroshima, BMC Pulmonary Medicine . 2019,第1期

机译：PD-L1，FGFR1，PIK3CA，PTEN和p16在肺气肿和慢性阻塞性肺疾病合并肺鳞癌中的表达
2. The effect of adipose derived stromal cells on oxidative stress level, lung emphysema and white blood cells of guinea pigs model of chronic obstructive pulmonary disease [J] . Ahmad Ghorbani, Azadeh Feizpour, Milad Hashemzahi, Daru Journal of pharmaceutical sciences. . 2014,第1期

机译：脂肪基质细胞对慢性阻塞性肺疾病豚鼠氧化应激水平，肺气肿和白细胞的影响
3. PIK3CA mutation as a distinctive genetic feature of non-small cell lung cancer with chronic obstructive pulmonary disease: A comprehensive mutational analysis from a multi-institutional cohort [J] . Kenji Sawa, Yasuhiro Koh, Tomoya Kawaguchi, Lung cancer: Journal of the International Association for the Study of Lung Cancer . 2017,第期

机译：Pik3CA突变作为非小型细胞肺癌的独特遗传特征，具有慢性阻塞性肺疾病：多机制队列的综合突变分析
4. Acrolein effects in pulmonary cells: relevance to chronic obstructive pulmonary disease [C] . Nadia Moretto, Giorgia Volpi, Fiorella Pastore, International Conference on Environmental Stressors in Biology and Medicine . 2012

机译：肺细胞中丙烯醛作用：与慢性阻塞性肺病的相关性
5. Providing ethical care: Cardiopulmonary Resuscitation (CPR) for Chronic Obstructive Pulmonary Disease (COPD) Exacerbations in Patients with End Stage Lung Disease (ESLD). [D] . Young, Jeanne. 2010

机译：提供伦理护理：心肺复苏术（CPR）用于终末期肺病（ESLD）患者的慢性阻塞性肺疾病（COPD）加重。
6. Basal Gene Expression by Lung CD4+ T Cells in Chronic Obstructive Pulmonary Disease Identifies Independent Molecular Correlates of Airflow Obstruction and Emphysema Extent [O] . Christine M. Freeman, Alexandra L. McCubbrey, Sean Crudgington, -1

机译：慢性阻塞性肺疾病中肺CD4 + T细胞的基础基因表达确定气流阻塞和肺气肿程度的独立分子相关性
7. PD-L1, FGFR1, PIK3CA, PTEN, and p16 expression in pulmonary emphysema and chronic obstructive pulmonary disease with resected lung squamous cell carcinoma [O] . Ken Arimura, Yasuo Sekine, Kenzo Hiroshima, 2019

机译：PD-L1，FGFR1，PIK3CA，PTEN和P16在肺气肿和慢性阻塞性肺病中表达，具有切除肺鳞状细胞癌

PD-L1 FGFR1 PIK3CA PTEN and p16 expression in pulmonary emphysema and chronic obstructive pulmonary disease with resected lung squamous cell carcinoma

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