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Clinical monitoring of cardiac output assessed by transoesophageal echocardiography in anaesthetised dogs: a comparison with the thermodilution technique

机译:经食道超声心动图评估麻醉犬心输出量的临床监测:与热稀释技术的比较

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摘要

BackgroundCardiac output (CO) is an important haemodynamic parameter to monitor in patients during surgery. However, the majority of the techniques for measuring CO have a limited application in veterinary practice due to their invasive approach and associated complexity and risks. Transoesophageal echocardiography (TEE) is a technique used to monitor cardiac function in human patients during surgical procedures and allows CO to be measured non-invasively. This prospective clinical study aimed to compare the transoesophageal echocardiography using a transgastric view of the left ventricular outflow tract (LVOT) and the thermodilution (TD) technique for the assessment of CO during mean arterial pressure of 65–80 mmHg (normotension) and <65 mmHg (hypotension) in dogs undergoing elective surgery. Eight dogs were pre-medicated with acepromazine (0.05 mg/kg, IM), tramadol (4 mg/kg, IM) and atropine (0.03 mg/kg, IM), followed by anaesthetic induction with propofol (3–5 mg/kg IV) and maintenance with isoflurane associated with a continuous infusion rate of fentanyl (bolus of 3 μg/kg followed by 0.3 μg/kg/min). The CO was measured by TEE (COTEE) and TD (COTD) at the end of expiration during normotension and hypotension (induced by isoflurane).
机译:背景心输出量(CO)是重要的血液动力学参数,可在手术期间监测患者。然而,由于其侵入性方法以及相关的复杂性和风险,大多数用于测量CO的技术在兽医实践中的应用受到限制。经食道超声心动图检查(TEE)是一种用于在外科手术过程中监测人类患者心脏功能的技术,可无创地测量CO。这项前瞻性临床研究旨在通过对左心室流出道(LVOT)和热稀释(TD)技术进行胃镜检查比较经食道超声心动图,以评估平均动脉压在65-80 mmHg(血压正常)和<65之间接受择期手术的狗的mmHg(低血压)。八只狗预先接受了醋丙嗪(0.05 mg / kg,IM),曲马多(4 mg / kg,IM)和阿托品(0.03 mg / kg,IM)的药物治疗,然后用异丙酚(3–5 mg / kg)麻醉诱导IV)并用异氟烷维持与芬太尼的连续输注速率有关(推注3μg/ kg,然后输注0.3μg/ kg / min)。在正常血压和低血压(由异氟烷引起)期满时,通过TEE(COTEE)和TD(COTD)测量CO。

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