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Case Report: Primary renal carcinoid tumour with lung metastasis misdiagnosed as renal cell carcinoma

机译:病例报告:原发性肾类癌合并肺转移误诊为肾细胞癌

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摘要

A 58-year-old man with a history of metastatic renal cell carcinoma (RCC) diagnosed 10 years prior, status post right nephrectomy, presented for evaluation of pulmonary nodules. A year after the nephrectomy, he had undergone cutaneous metastasectomy in the right flank area, and a further 2 years later he had had his second cutaneous metastasectomy in the right chest wall. Both cutaneous pathologies had, at the time, shown metastatic neoplasm with histological features compatible with those of the previous renal tumour. He was treated with sorafenib. 3 years later he developed asymptomatic pulmonary nodules, which gradually doubled in size over the next 2.5 years. He underwent bronchoscopy and left lower lobe biopsy. Pathology revealed a metastatic renal carcinoideuroendocrine tumour. Second review of the previous renal neoplasm and the cutaneous metastatic pathology showed trabecular architecture, consistent with carcinoid, but mimicking the long parallel arrays that have been described in some cases of papillary RCC.
机译:一名58岁的男性,有转移性肾细胞癌(RCC)病史,被诊断为右肾切除术后10年前,现被评估肺结节。肾切除术一年后,他在右胁腹区域进行了皮肤转移瘤切除术,再过2年后,他在右胸壁进行了第二次皮肤转移瘤切除术。当时,这两种皮肤病理都显示出转移性肿瘤,其组织学特征与先前的肾脏肿瘤相适应。他接受索拉非尼治疗。 3年后,他出现了无症状的肺结节,在接下来的2.5年中,其大小逐渐增加了一倍。他接受了支气管镜检查并左下叶活检。病理显示有转移性肾类癌/神经内分泌肿瘤。对先前的肾脏肿瘤和皮肤转移病理的第二次回顾显示,小梁结构与类癌一致,但模仿了在乳头状RCC病例中描述的长平行阵列。

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