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Population based assessment of uveitis in an urban population in southern India

机译:基于人口的印度南部城市人群葡萄膜炎评估

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摘要

AIM—To assess the prevalence of active and inactive uveitis unrelated to previous surgery or trauma in an urban population in southern India.
METHODS—As part of the Andhra Pradesh Eye Disease Study, 2522 subjects (85.4% of those eligible), a sample representative of the population of Hyderabad city in southern India, underwent interview and detailed dilated eye examination. Presence of sequelae of uveitis without current active inflammation was defined as inactive uveitis.
RESULTS—Unequivocal evidence of active or inactive uveitis unrelated to previous surgery or trauma was present in 21 subjects, an age-sex adjusted prevalence of 0.73% (95% confidence interval (CI) 0.44-1.14%). Active uveitis was present in eight subjects, an age-sex adjusted prevalence of 0.37% (95% CI 0.19-0.70), of which 0.06% was anterior, 0.25% intermediate, and 0.06% posterior. The 0.36% (95% CI 0.17-0.68%) prevalence of inactive uveitis included macular chorioretinitis scars (0.26%), anterior (0.07%) and previous vasculitis involving the whole eye (0.03%). The prevalence of visual impairment due to uveitis of less than 6/18 in at least one eye was 0.27%, less than 6/60 in at least one eye was 0.16%, and less than 6/60 in both eyes was 0.03%.
CONCLUSION—These population based cross sectional data give an estimate of the prevalence of various types of uveitis in this urban population in India. Active or past uveitis that might need treatment at some stage was present in one of every 140 people in this population.

机译:目的-评估与印度南部城市人群先前手术或创伤无关的活动性和非活动性葡萄膜炎的患病率。
方法-作为安得拉邦眼病研究的一部分,有2522名受试者(占合格者的85.4%) ,是印度南部海得拉巴市人口的样本代表,接受了采访和详细的散瞳检查。没有当前活动性炎症的葡萄膜炎后遗症被定义为非活动性葡萄膜炎。
结果-21个受试者中存在与先前手术或创伤无关的活动性或非活动性葡萄膜炎的明确证据,年龄性别校正后的患病率为0.73%( 95%置信区间(CI)0.44-1.14%)。活动性葡萄膜炎存在于八名受试者中,年龄性别调整的患病率为0.37%(95%CI 0.19-0.70),其中前者为0.06%,中位为0.25%,后者为0.06%。非活动性葡萄膜炎的患病率为0.36%(95%CI 0.17-0.68%),包括黄斑部脉络膜视网膜炎疤痕(0.26%),前眼部炎(0.07%)和先前的全眼累及的血管炎(0.03%)。在至少一只眼睛中,由于葡萄膜炎引起的视力损害的患病率小于0.27%,在至少一只眼睛中小于6/60的患病率为0.16%,并且两只眼睛中小于6/60的患病率为0.03%。
结论-这些基于人口的横断面数据对印度城市人口中各种类型葡萄膜炎的患病率进行了估算。该人群中每140个人中就有一个在某些阶段可能需要治疗的活动性或过去的葡萄膜炎。

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