Inter- and intra-observer variability of an anatomical landmark-based manual segmentation method by MRI for the assessment of skeletal muscle fat content and area in subjects from the general population

摘要

Objectives:Changes in skeletal muscle composition, such as fat content and mass, may exert unique metabolic and musculoskeletal risks; however, the reproducibility of their assessment is unknown. We determined the variability of the assessment of skeletal muscle fat content and area by MRI in a population-based sample.