ABCB1 polymorphisms may have a minor effect on ciclosporin blood concentrations in myasthenia gravis patients

机译：ABCB1基因多态性可能对重症肌无力患者的环孢素血药浓度有轻微影响

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WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT class="unordered" style="list-style-type:disc">Numerous studies have shown that MDR1 polymorphisms in the form of single nucleotide poymorphisms or haplptype affect ciclosporin pharmacokinetics or blood concentrations in organ transplantation patients, but some results conflict with others.

机译：关于此主题的已知信息 class =“ unordered” style =“ list-style-type：disc”> <！-list-behavior = unordered prefix-word = mark-type = disc max-label-size = 0-> 大量研究表明，单核苷酸多态性或单倍型形式的MDR1多态性会影响器官移植患者的环孢素药代动力学或血药浓度，但某些结果与其他结果相冲突。

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期刊名称 British Journal of Clinical Pharmacology
作者
Ya-tong Zhang; Li-ping Yang; Hong Shao; Ke-xin Li; Chun-hua Sun; Lu-wen Shi;
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作者单位

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年(卷),期 2008(66),2
年度 2008
页码 240–246
总页数 7
原文格式 PDF
正文语种
中图分类药学;
关键词
ABCB1 myasthenia gravis ciclosporin pharmacogenomics single nucleotide polymorphism blood concentrations;

机译：ABCB1;重症肌无力;环孢菌素;药物基因组学;单核苷酸多态性;血药浓度;

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专利

1. ABCB1 polymorphisms may have a minor effect on ciclosporin blood concentrations in myasthenia gravis patients. [J] . Zhang YT, Yang LP, Shao H, British Journal of Clinical Pharmacology . 2008,第2期

机译：ABCB1基因多态性可能对重症肌无力患者的环孢菌素血药浓度影响较小。
2. CYP3A5 and ABCB1 polymorphisms influence tacrolimus concentrations in peripheral blood mononuclear cells after renal transplantation. [J] . Capron A, Mourad M, De Meyer M, Pharmacogenomics . 2010,第5期

机译：CYP3A5和ABCB1多态性影响肾移植后外周血单核细胞中他克莫司的浓度。
3. ABCB1 polymorphisms and the concentrations of lopinavir and ritonavir in blood, semen and saliva of HIV-infected men under antiretroviral therapy [J] . Rita de Cassia Estrela, Fabio S Ribeiro, Paulo F Barroso, Pharmacogenomics . 2009,第2期

机译：抗逆转录病毒疗法下HIV感染男性血液，精液和唾液中ABCB1基因多态性与洛匹那韦和利托那韦浓度
4. Influence of CYP3A5 polymorphism on tacrolimus blood concentrations in renal transplant patients [C] . NIE Xin-min, GUI Rong, ZHAO Hong-shan, Postdoctoral Symposium for Celebration of 20th Anniversary of the Foundation of Chinese Postdoctoral System; 2005; . 2005

机译：CYP3A5基因多态性对肾移植患者他克莫司血药浓度的影响
5. Neoplastic epithelial cells express α-subunit of muscle nicotinic acetylcholine receptor in thymomas from patients with myasthenia gravis [D] . Hara, Yasuo 1991

机译：重症肌无力患者胸腺瘤中的肿瘤上皮细胞表达肌肉烟碱乙酰胆碱受体的α-亚基
6. Polymorphisms in ABCB1 and CYP19A1 genes affect anastrozole plasma concentrations and clinical outcomes in postmenopausal breast cancer patients [O] . Guillermo Gervasini, Carlos Jara, Clara Olier, 2017

机译：ABCB1和CYP19A1基因的多态性影响绝经后乳腺癌患者阿那曲唑的血药浓度和临床结局
7. ABCB1 polymorphisms may have a minor effect on ciclosporin blood concentrations in myasthenia gravis patients [O] . Zhang, Ya-tong, Yang, Li-ping, Shao, Hong, 2008

机译：ABCB1基因多态性可能对重症肌无力患者的环孢素血药浓度有轻微影响

ABCB1 polymorphisms may have a minor effect on ciclosporin blood concentrations in myasthenia gravis patients

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