When a placebo is not a ‘placebo’: a placebo effect on postprandial glycaemia

摘要

What is already known about this subject class="unordered" style="list-style-type:disc">Although placebo effects have been shown on subjective continuous variables such as pain, placebo effects on objective continuous variables remain uncertain.The present, pilot, follow-up investigation represents the first to assess a placebo effect on the objective continuous measurement of acute postprandial plasma glucose.What this study adds class="unordered" style="list-style-type:disc">Placebo effects may be operating on postprandial plasma glucose outcomes.Cornstarch sources of placebo may decrease the plasma glucose response to a 75-g oral glucose tolerance test, rendering them as positive controls when assessing postprandial outcomes.Other carbohydrate sources used as placebos in research may show similar effects.AimsPlacebo effects in clinical trials remain uncertain. To investigate a placebo effect on acute postprandial plasma glucose, we conducted a follow-up investigation on a previous study.