Relationship between the C3435T and G2677T(A) polymorphisms in the ABCB1 gene and P-glycoprotein expression in human liver

机译：ABCB1基因C3435T和G2677T（A）多态性与人肝P糖蛋白表达的关系

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摘要

AimsThe aim of the study was to determine whether a correlation exists between MDR1 (ABCB1) gene polymorphisms at positions 3435 (C3435T) and 2677 (G2677T(A)) and the expression of human hepatic P-glycoprotein (P-gp).

机译：目的研究的目的是确定在3435位（C3435T）和2677位（G2677T（A））的MDR1（ABCB1）基因多态性与人肝P-糖蛋白（P-gp）的表达之间是否存在相关性。

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期刊名称 British Journal of Clinical Pharmacology
作者
Andrew Owen; Chris Goldring; Paul Morgan; David Chadwick; B Kevin Park; Munir Pirmohamed;
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作者单位

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年(卷),期 2005(59),3
年度 2005
页码 365–370
总页数 6
原文格式 PDF
正文语种
中图分类药学;
关键词
ABCB1 C3435T expression G2677T/A MDR1 P-glycoprotein SNP;

机译：ABCB1;C3435T;表达;G2677T / A;MDR1;P糖蛋白;SNP;

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专利

1. Relationship between the C3435T and G2677T(A) polymorphisms in the ABCB1 gene and P-glycoprotein expression in human liver. [J] . Owen A, Goldring C, Morgan P, British Journal of Clinical Pharmacology . 2005,第3期

机译：ABCB1基因C3435T和G2677T（A）多态性与人肝P糖蛋白表达之间的关系。
2. Role of ABCB1 C1236T, G2677T, and C3435T genetic polymorphisms in the development of acute leukemia in a Chinese population [J] . R. Feng, H.X. Zhang, H.G. Zhang, Genetics and Molecular Research . 2016,第3期

机译：ABCB1 C1236T，G2677T和C3435T基因多态性在中国人群急性白血病发展中的作用
3. Association analysis of intractable epilepsy with C3435T and G2677T/A ABCB1 gene polymorphisms in Iranian patients. [J] . Sayyah M, Kamgarpour F, Maleki M, Epileptic disorders: international epilepsy journal with videotape . 2011,第2期

机译：伊朗患者顽固性癫痫与C3435T和G2677T / A ABCB1基因多态性的关联分析。
4. MDRView: a visualization of the polymorphisms of MDR1(ABCB1) GENE in breast cancer [C] . Xhemo E., Fajac A., Boire J.-Y., Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2007

机译：MDRView：乳腺癌中MDR1（ABCB1）基因多态性的可视化
5. In vitro Transport Profile of Antiepileptic Drugs by Human P-glycoprotein and Functional Evaluation of Human MDR1 Polymorphisms on Transport Activity. [D] . Zhang, Chunbo. 2011

机译：抗癫痫药通过人P糖蛋白的体外转运谱和人MDR1多态性对转运活性的功能评估。
6. Forced Expression of Heat Shock Protein 27 (Hsp27) Reverses P-Glycoprotein (ABCB1)-mediated Drug Efflux and MDR1 Gene Expression in Adriamycin-resistant Human Breast Cancer Cells [O] . Ragu Kanagasabai, Karthikeyan Krishnamurthy, Lawrence J. Druhan, 2011

机译：热休克蛋白27（Hsp27）的强制表达逆转P-糖蛋白（ABCB1）介导的药物外流和抗阿霉素的人乳腺癌细胞中的MDR1基因表达。
7. Relationship between the C3435T and G2677T(A) polymorphisms in the ABCB1 gene and P-glycoprotein expression in human liver [O] . Owen, Andrew, Goldring, Chris, Morgan, Paul, 2005

机译：ABCB1基因C3435T和G2677T（A）多态性与人肝P糖蛋白表达的关系

Relationship between the C3435T and G2677T(A) polymorphisms in the ABCB1 gene and P-glycoprotein expression in human liver

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