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Inhibition of the metabolism of brotizolam by erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in brotizolam metabolism

机译：红霉素对人的溴硝唑仑代谢的抑制作用：体内证据表明CYP3A4参与了溴硝唑仑的代谢

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摘要

AimsTo obtain in vivo evidence for the involvement of cytochrome P450 (CYP) 3A4 in the metabolism of brotizolam.

机译：目的获得体内证据证明细胞色素P450（CYP）3A4参与了brotizolam的代谢。

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期刊名称 British Journal of Clinical Pharmacology
作者
Takaki Tokairin; Takashi Fukasawa; Norio Yasui-Furukori; Toshiaki Aoshima; Akihito Suzuki; Yoshimasa Inoue; Tomonori Tateishi; Koichi Otani;
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作者单位

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年(卷),期 2005(60),2
年度 2005
页码 172–175
总页数 4
原文格式 PDF
正文语种
中图分类药学;
关键词
brotizolam CYP3A4 erythromycin metabolism;

机译：苯丁唑仑;CYP3A4;红霉素;代谢;

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专利

1. Inhibition of the metabolism of brotizolam by erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in brotizolam metabolism. [J] . Tokairin T, Fukasawa T, Yasui Furukori N, British Journal of Clinical Pharmacology . 2005,第2期

机译：红霉素对人的溴硝唑仑代谢的抑制作用：体内证据表明CYP3A4参与了溴硝唑仑的代谢。
2. Inhibition of the metabolism of etizolam by itraconazole in humans: evidence for the involvement of CYP3A4 in etizolam metabolism. [J] . Araki K, Yasui Furukori N, Fukasawa T, European journal of clinical pharmacology . 2004,第6期

机译：伊曲康唑对人的依替唑仑代谢的抑制作用：CYP3A4参与依替唑仑代谢的证据。
3. Inhibition of the metabolism of etizolam by itraconazole in humans: evidence for the involvement of CYP3A4 in etizolam metabolism [J] . K. Araki, N. Yasui-Furukori, T. Fukasawa, European Journal of Clinical Pharmacology . 2004,第6期

机译：伊曲康唑对人的依替唑仑代谢的抑制作用：CYP3A4参与依替唑仑代谢的证据
4. BINDING OF IMIDAZOLINONE HERBICIDES TO PLANT ACETOHYDROXYACID SYNTHASE IN VIVO, AND SECONDARY EFFECTS OF ENZYME INHIBITION ON METABOLISM [C] . D. L. Shaner, M. A. Stidham, M. J. Muhitch International Congress of Pesticide Chemistry . 1986

机译：咪唑啉酮除草剂对体内丙酮羟基酸合成酶的结合，以及酶抑制对代谢的二次影响
5. Two different aspects of cell metabolism: (i) Recovery from growth inhibition in vivo, and (ii) the biochemical consequences of a split gene [D] . Sabina, Jeffrey 2005

机译：细胞代谢的两个不同方面：（i）从体内生长抑制中恢复，以及（ii）分裂基因的生化后果
6. Pharmacokinetics and metabolism of brotizolam in humans [O] . W. D. Bechtel 1983

机译：布替唑仑在人体中的药代动力学和代谢
7. Inhibition of the metabolism of brotizolam by erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in brotizolam metabolism [O] . Tokairin, Takaki, Fukasawa, Takashi, Yasui-Furukori, Norio, 2005

机译：红霉素对人的溴硝唑仑代谢的抑制作用：体内证据表明CYP3A4参与了溴硝唑仑的代谢
8. Support of Study Entitled, 'Metabolism and Pharmacokinetics of Dihydroartemisinin' and 'In Vitro and In Vivo Metabolism of Sodium Artelinate and DQHS in Rats and Humans' [R] . Idowu, O. R. 1998

机译：支持研究题为“双氢青蒿素的代谢和药代动力学”和“大鼠和人类中的artelinate钠和DQHs的体外和体内代谢”

Inhibition of the metabolism of brotizolam by erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in brotizolam metabolism

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