Inhibition of the metabolism of etizolam by itraconazole in humans: evidence for the involvement of CYP3A4 in etizolam metabolism

K. Araki; N. Yasui-Furukori; T. Fukasawa; T. Aoshima; A. Suzuki; Y. Inoue; T. Tateishi; K. Otani

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Inhibition of the metabolism of etizolam by itraconazole in humans: evidence for the involvement of CYP3A4 in etizolam metabolism

机译：伊曲康唑对人的依替唑仑代谢的抑制作用：CYP3A4参与依替唑仑代谢的证据

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摘要

To clarify the involvement of cytochrome P 450 (CYP) 3A4 in the metabolism of etizolam.

机译：为了阐明细胞色素P 450 （CYP）3A4与依替拉姆的代谢有关。

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来源
《European Journal of Clinical Pharmacology》 |2004年第6期|427-430|共4页
作者
K. Araki; N. Yasui-Furukori; T. Fukasawa; T. Aoshima; A. Suzuki; Y. Inoue; T. Tateishi; K. Otani;
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作者单位

Department of Neuropsychiatry Yamagata University School of Medicine;

Department of Clinical Pharmacology Hirosaki University School of Medicine;

Department of Neuropsychiatry Yamagata University School of Medicine;

Department of Neuropsychiatry Yamagata University School of Medicine;

Department of Neuropsychiatry Yamagata University School of Medicine;

Pharmaceutical Research Division Mitsubishi Pharma;

Department of Clinical Pharmacology Hirosaki University School of Medicine;

Department of Neuropsychiatry Yamagata University School of Medicine;

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原文格式 PDF
正文语种 eng
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关键词
Etizolam; Itraconazole; CYP3A4;

机译：依替唑仑;伊曲康唑;CYP3A4;

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专利

1. Inhibition of the metabolism of etizolam by itraconazole in humans: evidence for the involvement of CYP3A4 in etizolam metabolism. [J] . Araki K, Yasui Furukori N, Fukasawa T, European journal of clinical pharmacology . 2004,第6期

机译：伊曲康唑对人的依替唑仑代谢的抑制作用：CYP3A4参与依替唑仑代谢的证据。
2. Inhibition of the metabolism of brotizolam by erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in brotizolam metabolism. [J] . Tokairin T, Fukasawa T, Yasui Furukori N, British Journal of Clinical Pharmacology . 2005,第2期

机译：红霉素对人的溴硝唑仑代谢的抑制作用：体内证据表明CYP3A4参与了溴硝唑仑的代谢。
3. Induction of the metabolism of etizolam by carbamazepine in humans. [J] . Kondo S, Fukasawa T, Yasui Furukori N, European journal of clinical pharmacology . 2005,第3期

机译：卡马西平在人体中诱导依替唑仑的代谢。
4. Pharmacokinetic model for the inhibition of simvastatin metabolism by itraconazole [C] . Lohitnavy Manupat, Methaneethorn Janthima, Chiang-Ngernthanyakool Rangsimaporn, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2015

机译：伊曲康唑抑制辛伐他汀代谢的药代动力学模型
5. Contribution of itraconazole and its metabolites to in vivo CYP3A4 inhibition. [D] . Templeton, Ian Edward. 2009

机译：伊曲康唑及其代谢物对体内CYP3A4抑制的作用。
6. Inhibition of the metabolism of brotizolam by erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in brotizolam metabolism [O] . Takaki Tokairin, Takashi Fukasawa, Norio Yasui-Furukori, 2005

机译：红霉素对人的溴硝唑仑代谢的抑制作用：体内证据表明CYP3A4参与了溴硝唑仑的代谢
7. Inhibition of the metabolism of brotizolam by erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in brotizolam metabolism [O] . Tokairin, Takaki, Fukasawa, Takashi, Yasui-Furukori, Norio, 2005

机译：红霉素对人的溴硝唑仑代谢的抑制作用：体内证据表明CYP3A4参与了溴硝唑仑的代谢
8. Metabolism of Endosulfan-Alpha by Human Liver Microsomes and its Utility as a Simultaneous In Vitro Probe for CYP2B6 and CYP3A4 [R] . Casabar, R. C. , Wallace, A. D. , Hodgson, E. , 2006

机译：人肝微粒体对硫丹-α的代谢及其作为CYp2B6和CYp3a4同时体外探针的应用

Inhibition of the metabolism of etizolam by itraconazole in humans: evidence for the involvement of CYP3A4 in etizolam metabolism

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