Saccadic eye movement analysis as a measure of drug effects on human psychomotor performance

摘要

>1 Analysis of human horizontal saccadic eye movements can provide measurements of central nervous system depression and stimulation.>2 Effects on saccadic eye movements have been observed in normal volunteers with barbiturates, benzodiazepines, opiates and related compounds, carbamazepine, amphetamine and ethanol.>3 A suite of programmes have been developed to allow the generation, collection and analysis of saccadic eye movements using a CBM 3032, 8032 or BBC B microcomputer. The system allows almost continuous sampling and rapid analysis of movements.