1. Systolic time intervals (STI) were recorded in six normal male subjects over a period of 3 weeks. On one day per week, each subject received incremental doses of atropine intravenously to increase heart rate, allowing the determination of individual STI v HR regression equations. On the other days STI were recorded with the subjects resting, in the supine position. 2. There were highly significant regression relationships between heart rate and both LVET and QS2, but not between heart rate and PEP. 3. The regression relationships showed little intra-subject variability, but a large degree of inter-subject variability: they proved adequate to correct the STI for the daily fluctuations in heart rate. 4. Administration of small doses of atropine intravenously provides a satisfactory and convenient method of deriving individual STI v HR regression equations which can be applied over a period of weeks.
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机译:1.在3周内记录了6名正常男性受试者的收缩期间隔(STI)。每周有一天,每位受试者静脉内接受递增剂量的阿托品以增加心率,从而确定各个STI v HR回归方程。在其他日子,记录了STI,使受试者仰卧休息。 2.心率与LVET和QS2之间存在高度显着的回归关系,但心率与PEP之间无显着回归关系。 3.回归关系显示出受试者间的变异性很小,但受试者间的变异性却很大:它们被证明足以校正每日心率波动的STI。 4.静脉内小剂量阿托品给药可提供令人满意且方便的方法,以推导可在数周内应用的单个STI v HR回归方程。
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