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Piloting the Affordable Medicines Facility-malaria: what will success look like?

机译:试行可负担药物设施疟疾:成功将是什么样?

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摘要

The Affordable Medicines Facility-malaria is an innovative financing mechanism, managed by the Global Fund to Fight AIDS, Tuberculosis and Malaria. This initiative aims to increase the use of artemisinin-based combination therapies for treating malaria. A pilot is underway in eight countries to determine whether the mechanism reduces the consumer price of these drugs and increases their availability in public and private outlets, their market share and their use. To evaluate the pilot, an analysis was done to estimate predetermined “benchmarks” of success at 1 and 2 years. The analysis used a mixed-methods approach, triangulating data from a literature review with information from 33 interviews with experts. A sensitivity analysis and other methods were used to verify the results. Benchmarks used to determine success include an increase in availability of artemisinin-based combination therapies of 40 percentage points from baseline, and an increase in their use of 10–15 percentage points from baseline at year 2. These benchmarks were based on evidence that national public health programmes aimed at increasing the use of a specific health commodity in developing countries have generally achieved only modest changes in use within a 2-year time frame. Evaluation should also take individual country contexts into account.
机译:负担得起的药品基金-疟疾是一种创新的筹资机制,由全球抗击艾滋病,结核病和疟疾基金管理。该计划旨在增加基于青蒿素的联合治疗疟疾的使用。目前正在八个国家进行一项试验,以确定该机制是否降低了这些药物的消费价格,并增加了它们在公共和私人商店的可获得性,其市场份额和使用情况。为了评估飞行员,进行了分析以估计在1年和2年时成功的预定“基准”。分析使用混合方法,将来自文献综述的数据与来自33位专家访谈的信息进行了三角剖分。使用敏感性分析和其他方法来验证结果。用来确定成功的基准包括在第2年时基于青蒿素的联合疗法的可用性比基线增加40个百分点,以及它们从基线的使用率比基线增加10-15个百分点。这些基准基于国家公众的证据旨在在发展中国家增加对特定保健商品的使用的保健计划,总体而言,在2年的时间范围内仅实现了适度的使用变化。评价还应考虑到各个国家的情况。

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