Augmentation of Sodium Butyrate-induced Apoptosis by Phosphatidylinositol 3-kinase Inhibition in the Human Cervical Cancer Cell-line

机译：在人宫颈癌细胞株中磷酸丁酯醇3-激酶抑制增强丁酸钠诱导的细胞凋亡。

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PurposeSodium butyrate (NaBT) is principally a histone deacetylase (HDAC) inhibitor, and it has the potential to arrest HPV-positive carcinoma cells at the G1 to S phase transition of the cell cycle. The aim of study was to determine whether phosphatidylinositol 3-kinase (PI3K) inhibition can enhance the inhibitory effect of NaBT on a human cervical cancer cell line (HeLa).

机译：目的丁酸钠（NaBT）主要是组蛋白脱乙酰基酶（HDAC）抑制剂，它具有在细胞周期的G1到S期转变中阻止HPV阳性癌细胞的潜能。研究的目的是确定磷脂酰肌醇3-激酶（PI3K）抑制是否可以增强NaBT对人宫颈癌细胞系（HeLa）的抑制作用。

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期刊名称 Cancer Research and Treatment : Official Journal of Korean Cancer Association
作者
Jung Kyu Park; Chi Heum Cho; Sabarish Ramachandran; So Jin Shin; Sang Hoon Kwon; Sun Young Kwon; Soon Do Cha;
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作者单位

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年(卷),期 2006(38),2
年度 2006
页码 112–117
总页数 6
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Cervical cancer Sodium butyrate Phosphatidylinositol 3-kinase Apoptosis;

机译：宫颈癌;丁酸钠;磷脂酰肌醇3-激酶;细胞凋亡;

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专利

1. Augmentation of Sodium Butyrate-Induced Apoptosis by p38 MAP Kinase Inhibition in Rat Liver Epithelial Cells. [J] . Jung JW, Cho SD, Ahn NS, Antioxidants and redox signalling . 2005,第11a12期

机译：通过p38 MAP激酶抑制作用增强大鼠肝上皮细胞中丁酸钠诱导的细胞凋亡。
2. Galangin Induces Apoptosis in MCF-7 Human Breast Cancer Cells Through Mitochondrial Pathway and Phosphatidylinositol 3-Kinase/Akt Inhibition [J] . Liu Dan, You Pengtao, Luo Yan, Pharmacology: International Journal of Experimental and Clinical Pharmacology . 2018,第1a2期

机译：Galangin通过线粒体途径和磷脂酰肌醇3-激酶/ akt抑制诱导MCF-7人乳腺癌细胞的细胞凋亡
3. Inhibition of Phosphatidylinositol 3-Kinase Amplifies TEGDMA-induced Apoptosis in Primary Human Pulp Cells. [J] . Spagnuolo G, Galler K, Schmalz G, Journal of Dental Research: Official Publication of the International Association for Dental Research . 2004,第9期

机译：磷脂酰肌醇3-激酶的抑制作用会放大TEGDMA诱导的原代人浆细胞凋亡。
4. Proliferation inhibition and apoptosis induction of Juglone on human cervical cancer HeLa cells [C] . Wei Zhang, Wenhe Zhu, Yan Li, International Conference on Frontiers of Advanced Materials and Engineering Technology . 2014

机译：juglone对人宫颈癌Hela细胞的增殖抑制和凋亡诱导
5. The anti-cancer activities of Paeoniae Radix extracts on human hepatocellular carcinoma cell-line HepG2 and multidrug resistant human hepatocellular carcinoma cell-line R-HepG2 and their action mechanisms. [D] . Li, Lok Yee Mandy. 2004

机译：e药提取物对人肝癌细胞HepG2和多药耐药人肝癌细胞R-HepG2的抗癌活性及其作用机制。
6. Sodium butyrate-induced DAPK-mediated apoptosis in human gastric cancer cells [O] . HYUNSOO SHIN, YEO SONG LEE, YONG CHAN LEE -1

机译：丁酸钠诱导DAPK介导的人胃癌细胞凋亡
7. Augmentation of Sodium Butyrate-induced Apoptosis by Phosphatidylinositol 3-kinase Inhibition in the Human Cervical Cancer Cell-line [O] . Park, Jung Kyu, Cho, Chi Heum, Ramachandran, Sabarish, 2006

机译：在人类宫颈癌细胞株中磷酸丁酯醇3-激酶抑制增强丁酸钠诱导的细胞凋亡。

Augmentation of Sodium Butyrate-induced Apoptosis by Phosphatidylinositol 3-kinase Inhibition in the Human Cervical Cancer Cell-line

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