Intracardiac Thrombus in Leukemia: Role of Cardiac Magnetic Resonance Imaging in Eosinophilic Myocarditis

摘要

class="kwd-title">Keywords: Intracardiac thrombus, Cardiac magnetic resonance imaging, Hypereosinophilic syndrome, Eosinophilic myocarditis class="head no_bottom_margin" id="sec1title">IntroductionHypereosinophilic syndrome (HES) is defined as an absolute eosinophil count > 1.5 × 10⁹/L on two separate examinations separated by at least 1 month and/or pathologic tissue confirmation with evidence of end organ damage in the absence of any known cause of hypereosinophilia. HES is a rare condition with unknown prevalence and is subclassified into primary, secondary, or idiopathic. Primary HES occurs in the setting of stem cell, myeloid, or eosinophilic neoplasm. Secondary HES is a reactive process due to parasitic infections, certain solid tumors, and T-cell lymphoma. Patients are usually diagnosed between 20 and 50 years of age, but HES can also be seen in children., , In all classes, eosinophils infiltrate and damage common target organs that can include the pulmonary system (Loeffler's syndrome) and/or the cardiovascular system, resulting in eosinophilic myocarditis (EM).