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Purpura Fulminans and Septic Shock due to Capnocytophaga Canimorsus after Dog Bite: A Case Report and Review of the Literature

机译:犬咬伤后因Capnocytophaga Canimorsus引起的紫癜和败血性休克:一例病例报告并文献复习

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摘要

Primary infection by Capnocytophaga canimorsus after dog bite is rare but may be difficult to identify and rapidly lethal. We describe a case of fatal septic shock with fulminant purpura occurred in a patient without specific risk factor two days after an irrelevant dog bite. The patient was brought to hospital because of altered mental status, fever, and abdominal pain. In a few hours patient became hypoxic and cyanotic. The patient became extremely hypotensive with shock refractory to an aggressive fluid resuscitation (40 ml/kg crystalloids). She received vasoactive drugs, antibiotic therapy, and blood purification treatment, but cardiac arrest unresponsive to resuscitation maneuvers occurred. Case description and literature review demonstrated that, also in patients without specific risk factors, signs of infection after dog bite should be never underestimated and should be treated with a prompt antibiotic therapy initiation even before occurrence of organ dysfunction.
机译:犬咬伤后由犬毛细单胞菌引起的原发感染极少见,但可能难以识别并迅速致死。我们描述了在不相关的狗咬伤后两天,在没有特定危险因素的患者中发生致命性脓毒性休克伴暴发性紫癜的情况。该患者因精神状态改变,发烧和腹痛而被送往医院。几个小时后,病人变得缺氧和发cyan。病人血压极低,因激进的液体复苏而使休克难治(40μml/ kg晶体)。她接受了血管活性药物,抗生素治疗和血液净化治疗,但发生了对复苏动作无反应的心脏骤停。病例描述和文献综述表明,在没有特定危险因素的患者中,切勿低估被狗咬伤后的感染迹象,甚至应在出现器官功能障碍之前立即进行抗生素治疗。

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