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Electrocardiographic changes in a rare case of flecainide poisoning: a case report

机译:罕见的氟卡尼中毒病例的心电图改变:一例报告

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摘要

Flecainide is a class Ic anti - arrhythmic drug with sodium channel blocking activities. We report a case of a 57 year - old woman who attempted a suicide by ingesting approximately 1,8 gr of flecainide. On the surface electrocardiogram this results in a large QRS complex and in prolongation of the QTc interval. Overdose with a class Ic drug is very uncommon, its management is difficult and the mortality high.Because of a hemodynamic instability and in addition to supportive care and antidysrhythmics, she was treated with a high dose of sodium bicarbonate in hypertonic solution; after this infusion the patient's QRS progressive narrowed.In conclusion, sodium bicarbonate may be useful in the treatment of widened QRS and to stabilize a overdose of class Ic anti - arrhythmic drugs.
机译:氟卡尼特是一种具有钠通道阻滞活性的Ic类抗心律不齐药物。我们报告了一例57岁的老妇,他通过摄入约1.8克氟卡尼企图自杀。在表面心电图上,这会导致QRS复杂,QTc间隔延长。过量服用Ic类药物非常少见,治疗困难且死亡率高。由于血液动力学不稳定,除支持治疗和抗心律失常外,她还在高渗溶液中用了大剂量碳酸氢钠治疗;输注后,患者的QRS进行性逐渐变窄。总之,碳酸氢钠可用于治疗扩大的QRS并稳定过量的Ic类抗心律不齐药物。

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