Vitrification and Subsequent In Vitro Maturationof Mouse Preantral Follicles in Presenceof Growth Factors

摘要

ObjectiveCryopreservation of ovarian tissue or follicles has been proposed as an alternative method for fertility preservation. Although successful vitrification of follicles has been reported in several mammalian species, the survival rate is generally low. The aim of this study was to investigate the effects of fibroblast growth factor (FGF) and epidermal growth factor (EGF) on in vitro preantral follicle development after vitrification.