The Effect of Melatonin on Maturation GlutathioneLevel and Expression of H MGB1 Gene in BrilliantCresyl Blue (BCB) Stained Immature Oocyte

摘要

Objective:Nutrients and antioxidants in the medium of immature oocyte have a profound effect on maturation, fertilization and development of resulting embryos. In this study the effects of melatonin as an antioxidant agent on maturation, glutathione level and expression of High mobility group box-1 (HMGB1) gene were evaluated in immature oocytes of mice stained with brilliant cresyl blue (BCB).