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Severe Myopericarditis in Diabetic Ketoacidosis—All Troponin are Not Myocardial Infarction

机译:糖尿病性酮症酸中毒中的严重心律失常—所有肌钙蛋白都不是心肌梗塞

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摘要

Uncontrolled diabetes and acute coronary syndrome share a complex dynamic that results in significant ambiguity when interpreting biomarker elevations in this setting. This is concerning because myocardial infarction has been shown to be the most common cause of death in the first 24 hours of admission for uncontrolled diabetes. Literature shows that elevation in cardiac biomarkers in patients with uncontrolled diabetes could be from viral myopericarditis, although a clear clinical significance is still lacking.1 It is, however, clear that elevation in cardiac biomarkers portends a poor long-term prognosis in patients with uncontrolled diabetes mellitus. We present a rare case of myopericarditis in a middle-aged patient with uncontrolled diabetes. The patient had elevated troponin I level reaching a peak of 7.3 ng/mL with associated ST elevations on electrocardiography. Coronary angiogram was subsequently done revealing clean coronaries. To our knowledge, this is the first description of myopericarditis in uncontrolled diabetes without a known cause.
机译:不受控制的糖尿病和急性冠状动脉综合征具有复杂的动态关系,在这种情况下解释生物标志物升高时会导致明显的歧义。这是令人担忧的,因为在未控制的糖尿病患者入院后的最初24小时内,心肌梗死已被证明是最常见的死亡原因。文献表明,尽管仍缺乏明确的临床意义,但糖尿病糖尿病患者不受控制的心脏生物标志物升高可能是由于病毒性心律失常引起的。 1 然而,很明显,心脏生物标志物升高预示着长期的不良后果。失控的糖尿病患者的长期预后。我们目前在患有中风的糖尿病中年患者中罕见的肌心包炎病例。该患者的肌钙蛋白I水平升高,达到7.3 ng / mL的峰值,心电图检查提示ST升高。随后进行了冠状动脉造影,显示出干净的冠状动脉。据我们所知,这是在没有已知原因的不受控制的糖尿病中对肌心炎的首次描述。

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