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A Pooled Analysis of Two Multicenter Randomized Controlled Trials of a Single Intra-articular Injection of Gel-200 for Treatment of Osteoarthritis of the Knee

机译：一次关节腔内注射Gel-200治疗膝骨关节炎的两个多中心随机对照试验的汇总分析

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摘要

Background and Objective:To perform an integrated analysis of 2 randomized controlled trials (RCTs) to assess the efficacy and safety of a single intra-articular injection of Gel-200 compared with phosphate buffered saline (PBS) for treatment of osteoarthritis of the knee.

机译：背景与目的：对两项随机对照试验（RCT）进行综合分析，以评估单次关节腔内注射Gel-200与磷酸盐缓冲液（PBS）相比治疗膝部骨关节炎的有效性和安全性。

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期刊名称 Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
作者
Junko Takamura; Takayuki Seo; Vibeke Strand;
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作者单位

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年(卷),期 2018(11),-1
年度 2018
页码 1179544118773068
总页数 6
原文格式 PDF
正文语种
中图分类外科学 ;
关键词
Osteoarthritis knee intra-articular cross-linked HA Gel-200;

机译：骨关节炎;膝盖;关节内;交联的HA;Gel-200;

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专利

1. A Single Intra-Articular Injection of Gel-200 for Treatment of Symptomatic Osteoarthritis of the Knee Is More Effective than Phosphate Buffered Saline at 6 Months: A Subgroup Analysis of a Multicenter, Randomized Controlled Trial [J] . Takamura Junko, Seo Takayuki, Strand Vibeke Cartilage . 2019 ,第4期

机译：用于治疗膝关节骨关节炎的单个关节内注射凝胶 - 膝关节骨关节炎更有效，在6个月内比磷酸盐缓冲盐水更有效：多中心，随机对照试验的亚组分析
2. A multicenter, randomized controlled trial comparing a single intra-articular injection of Gel-200, a new cross-linked formulation of hyaluronic acid, to phosphate buffered saline for treatment of osteoarthritis of the knee [J] . StrandV., BarafH.S.B., LavinP.T., Osteoarthritis and cartilage . 2012 ,第5期

机译：一项多中心随机对照试验，比较了关节腔内单次注射Gel-200（一种新的透明质酸交联剂）与磷酸盐缓冲液治疗膝盖骨关节炎的情况
3. A single intra-articular injection of 2.0% non-chemically modified sodium hyaluronate vs 0.8% hylan G-F 20 in the treatment of symptomatic knee osteoarthritis: A 6-month, multicenter, randomized, controlled non-inferiority trial [J] . Emmanuel Maheu, Bernard Avouac, Renée Liliane Dreiser, PLoS One . 2019 ,第12期

机译：单个关节内注射2.0％非化学改性透明质酸钠与0.8％Hylan G-F 20在症状膝关型骨关节炎的治疗中：6个月，多中心，随机，受控的非劣级审判
4. Effects of 650 nm-10.6 μm Combined Laser Acupuncture-Moxibustion on Knee Osteoarthritis:A Randomized,Double-blinded and Placebo-controlled Clinical Trial [C] . SHEN Xue-yong, DING Guang-hong, WU Fan, The 3rd Workshop on Scientific Approaches to Chinese Medicine(第三届中医科学研究方法研讨会)论文集 . 2008

机译：650 nm-10.6μm联合激光针灸对膝骨关节炎的影响：一项随机，双盲和安慰剂对照的临床试验
5. Efficacy of glucosamine sulfate in knee osteoarthritis: A randomized controlled discontinuation trial. [D] . Cibere, Jolanda. 2004

机译：氨基葡萄糖硫酸盐在膝骨关节炎中的功效：一项随机对照停药试验。
6. A Single Intra-Articular Injection of Gel-200 for Treatment of Symptomatic Osteoarthritis of the Knee Is More Effective than Phosphate Buffered Saline at 6 Months: A Subgroup Analysis of a Multicenter Randomized Controlled Trial [O] . Junko Takamura, Takayuki Seo, Vibeke Strand 2019

机译：在六个月时单次关节腔内注射Gel-200治疗膝部症状性骨关节炎比磷酸盐缓冲盐水更有效：多中心随机对照试验的亚组分析
7. A Single Intra-Articular Injection of Gel-200 for Treatment of Symptomatic Osteoarthritis of the Knee Is More Effective than Phosphate Buffered Saline at 6 Months: A Subgroup Analysis of a Multicenter, Randomized Controlled Trial [O] . Junko Takamura, Takayuki Seo, Vibeke Strand 2018

机译：用于治疗膝关节骨关节炎的单个关节内注射凝胶 - 膝关节骨关节炎更有效，在6个月内比磷酸盐缓冲盐水更有效：多中心，随机对照试验的亚组分析

A Pooled Analysis of Two Multicenter Randomized Controlled Trials of a Single Intra-articular Injection of Gel-200 for Treatment of Osteoarthritis of the Knee

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