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Efficacy and safety of sofosbuvir-based regimens for treatment in chronic hepatitis C genotype 1 patients with moderately impaired renal function

机译：索非布韦为基础的治疗方案在慢性肾功能不全的慢性丙型肝炎患者中的疗效和安全性

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Background/AimsTreatment of chronic hepatitis C virus (HCV) infection in patients with chronic kidney disease (CKD) is essential. The availability of sofosbuvir (SOF) has dramatically improved overall HCV cure rates, however there is insufficient data regarding its use in patients with CKD. We evaluated SOF in patients with hepatitis C genotype 1 (G1) and moderately impaired renal function.

机译：背景/目的治疗慢性肾病（CKD）患者的慢性丙型肝炎病毒（HCV）感染至关重要。索非布韦（SOF）的使用已大大提高了HCV的总体治愈率，但是，有关在CKD患者中使用它的数据还不足。我们评估了丙型肝炎基因型1（G1）和肾功能中度受损的患者的SOF。

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期刊名称 Clinical and Molecular Hepatology
作者
Hyun Phil Shin; Ji-Ae Park; Blaire Burman; Richard A. Kozarek; Asma Siddique;
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作者单位

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年(卷),期 2017(23),4
年度 2017
页码 316–322
总页数 7
原文格式 PDF
正文语种
中图分类分子生物学;
关键词
Sofosbuvir Chronic kidney diseases Hepatitis C Safety;

机译：Sofosbuvir;慢性肾脏疾病;丙型肝炎;安全性;

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专利

1. Safety of Sofosbuvir-Based Regimens for the Treatment of Chronic HCV Infection in Patients with Mild or Moderate Renal Impairment [J] . Durand Francois, Pianko Stephen, Ni Liyun, Hepatology: Official Journal of the American Association for the Study of Liver Diseases . 2016,第S1期

机译：基于Sofosbuvir的安全性治疗温和或中等肾损伤患者慢性HCV感染的方案
2. Paritaprevir/Ritonavir/Ombitasvir Plus Dasabuvir Regimen in the Treatment of Genotype 1 Chronic Hepatitis C Infection in Patients with Severe Renal Impairment and End-Stage Renal Disease: a Real-Life Cohort [J] . Sperl J., Kreidlova M., Merta D., Kidney and blood pressure research . 2018,第2期

机译：Paritaprevir / Ritonavir / Ombitasvir加Dasabuvir方案在严重肾功能不全和终末期肾脏疾病患者的基因型1型慢性丙型肝炎感染中的治疗：一项真实的队列研究
3. Treatment of hepatitis C patients in a public health care setting with sofosbuvir-based treatment regimens: Efficacy and safety in real-life in Punjab, India [J] . Dhiman Radha K., Grover Gagandeep S., Satsangi Sandeep, Hepatology: Official Journal of the American Association for the Study of Liver Diseases . 2017,第Suppla1期

机译：用基于Sofosbuvir的治疗方案进行丙型肝炎患者丙型肝炎患者：印度旁遮普邦旁遮普实际的疗效和安全性
4. Efficacy of Chronic Hepatitis C Treatment in Hemophilic Patients During the Last 10 Years: a Single Center Experience [C] . P. Smejkal, P. Husa, M. Matyskova, Hemophilia Symposium . 2008

机译：慢性丙型肝炎治疗在过去10年中血友病患者的疗效：单一中心经验
5. Population pharmacokinetics and efficacy of ribavirin in patients with chronic hepatitis C genotype 1 infection. [D] . Jin, Runyan. 2010

机译：利巴韦林在慢性丙型肝炎基因型1感染患者中的群体药代动力学和功效。
6. Efficacy and safety outcomes of sofosbuvir-based treatment regimens for hepatitis C virus-infected patients with or without cirrhosis from phase III clinical trials [O] . Young-Mo Yang, Eun Joo Choi 2017

机译：基于Sofosbuvir的治疗方案对丙型肝炎病毒感染的肝硬化或非肝硬化患者的疗效和安全性来自III期临床试验
7. Efficacy and safety of sofosbuvir-based regimens for treatment in chronic hepatitis C genotype 1 patients with moderately impaired renal function [O] . Hyun Phil Shin, Ji-Ae Park, Blaire Burman, 2017

机译：基于sofosbuvir的方案治疗慢性丙型肝炎基因1型中度肾功能不全患者的疗效和安全性

Efficacy and safety of sofosbuvir-based regimens for treatment in chronic hepatitis C genotype 1 patients with moderately impaired renal function

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