Antiemesis After Total Joint Arthroplasty: Does a Single Preoperative Dose of Aprepitant Reduce Nausea and Vomiting?

机译：全关节置换术后的呕吐：术前单一剂量的阿瑞吡坦是否会减少恶心和呕吐？

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BackgroundPostoperative nausea and vomiting (PONV) is frequent after joint arthroplasty; in addition to causing patient distress, it interferes with early mobilization and hospital discharge. Various antiemetic agents reduce PONV, but their action is limited by a short half-life. Aprepitant, an antiemetic developed for patients receiving chemotherapy, has a duration of action much longer than other antiemetics.

机译：背景关节置换术后经常发生恶心和呕吐（PONV）。除了使患者感到困扰之外，它还会干扰早期动员和出院。各种止吐药可降低PONV，但其作用受到半衰期短的限制。 Aprepitant是为接受化疗的患者开发的止吐药，其作用持续时间比其他止吐药长得多。

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期刊名称 Clinical Orthopaedics and Related Research
作者
Timothy M. DiIorio; Peter F. Sharkey; Agnes M. Hewitt; Javad Parvizi;
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年(卷),期 2010(468),9
年度 2010
页码 2405–2409
总页数 5
原文格式 PDF
正文语种
中图分类外科学;矫形学;
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专利

1. Antiemesis after total joint arthroplasty: does a single preoperative dose of aprepitant reduce nausea and vomiting? [J] . DiIorio TM, Sharkey PF, Hewitt AM, Clinical Orthopaedics and Related Research . 2010,第9期

机译：全关节置换术后的呕吐：术前单一剂量的阿瑞吡坦是否能减轻恶心和呕吐？
2. Antiemesis After Total Joint Arthroplasty: Does a Single Preoperative Dose of Aprepitant Reduce Nausea and Vomiting? [J] . Timothy M. DiIorio, Peter F. Sharkey, Agnes M. Hewitt, Clinical Orthopaedics and Related Research® . 2010,第9期

机译：全关节置换术后的呕吐：术前单一剂量的阿瑞吡坦是否会减少恶心和呕吐？
3. Effects of preoperative, scheduled administration of antiemetics in reducing postoperative nausea and vomiting in patients undergoing total knee arthroplasty [J] . Hyung Jun Park, Moon Jong Chang, Seung-Baik Kang, Medicine. . 2021,第1期

机译：术前，预定施用止血剂术后恶心术后恶心，呕吐术后膝关节关节置换术
4. Therapy Acupressure to Reduce Nausea and Vomiting of Post General Anesthesia in RSUD Wates Kulon Progo [C] . Induniasih, Ana Ratnawati, Mona Indah Muntholib International Conference on Health Sciences . 2019

机译：治疗术治疗Rsud Wates Kulon Progo中的全身麻醉后恶心和呕吐
5. The effectiveness of a preoperative multimodal antiemetic regimen on reducing early postoperative nausea and vomiting in total joint arthroplasty patients [D] . Mosley, Jerry, Jr. 2015

机译：术前多模式止吐方案对减少全关节置换患者术后早期恶心和呕吐的有效性
6. A randomized phase III study evaluating the efficacy of single-dose NEPA a fixed antiemetic combination of netupitant and palonosetron versus an aprepitant regimen for prevention of chemotherapy-induced nausea and vomiting (CINV) in patients receiving highly emetogenic chemotherapy (HEC) [O] . L Zhang, S Lu, J Feng, -1

机译：一项III期随机研究评估单剂量NEPAnetupitant和palonosetron的固定止吐药与预防性方案在接受高促发性化疗（HEC）的患者中预防化疗引起的恶心和呕吐（CINV）的疗效
7. Antiemesis After Total Joint Arthroplasty: Does a Single Preoperative Dose of Aprepitant Reduce Nausea and Vomiting? [O] . DiIorio, Timothy M., Sharkey, Peter F., Hewitt, Agnes M., 2010

机译：全关节置换术后的呕吐：术前单一剂量的阿瑞吡坦是否会减少恶心和呕吐？

Antiemesis After Total Joint Arthroplasty: Does a Single Preoperative Dose of Aprepitant Reduce Nausea and Vomiting?

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