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Fibrinolytic Treatment after Transient Ischaemic Attack Caused by Prosthetic Mitral Valve Thrombosis

机译:人工二尖瓣血栓形成引起的短暂性脑缺血发作后的纤溶治疗

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摘要

Prosthetic valve thrombosis is one of the most severe complications after surgical valve replacement. There are many possible presentations: from asymptomatic to life-threatening complications. We report on a 61-year-old female patient with prosthetic replacement of the aortic and mitral valve in the in-house department of cardiac surgery 3 months ago. The patient was suffering from aphasia during 5 minutes in domesticity. After her presentation in the emergency room, the echocardiographic examination revealed a thrombotic formation of the prosthetic mitral valve. At presentation, the anticoagulation was outside the effective range (INR: 1.7). A successful thrombolytic therapy with the plasminogen activator urokinase was begun with complete resolution of the thrombus.
机译:人工瓣膜血栓形成是外科瓣膜置换术后最严重的并发症之一。有许多可能的表现:从无症状到危及生命的并发症。我们在3个月前的内部心脏外科部门报告了一名61岁的女性患者,该患者接受了人工置换的主动脉和二尖瓣。该患者在家中5分钟内患有失语症。在急诊室就诊后,超声心动图检查发现了人工二尖瓣的血栓形成。目前,抗凝治疗不在有效范围内(INR:1.7)。用纤溶酶原激活剂尿激酶成功进行溶栓治疗后,血栓完全消失。

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