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Clinical Conundrums in the Management of Diabetic Ketoacidosis in the Elderly

机译:老年糖尿病性酮症酸中毒的临床难题

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摘要

One of the dreaded life-threatening complications of diabetes mellitus (DM) is diabetic ketoacidosis (DKA). American Diabetic Association (ADA) came out with 2018 guidelines on the management of DM and its complications, but these are woefully silent on the clinical conundrums that accompany DKA in elderly patients. In elderly patients, DKA is often complicated by sepsis, atrial fibrillation, polypharmacy, nonketotic hyperosmolar states, atypical clinical presentations, acute kidney injury (AKI), dementia, and noncompliance with medications. Here in we highlight these conundrums that need to be addressed to improve morbidity and mortality in elderly patients.
机译:可怕的威胁生命的糖尿病并发症(DM)是糖尿病性酮症酸中毒(DKA)。美国糖尿病协会(ADA)提出了2018年有关DM及其并发症的治疗指南,但这些指南对老年患者伴随DKA的临床难题深表遗憾。在老年患者中,DKA常常并发败血症,房颤,多药,非酮症性高渗状态,非典型临床表现,急性肾损伤(AKI),痴呆和不遵从药物。在这里,我们强调了这些难题,需要改善老年患者的发病率和死亡率。

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