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Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation migration and invasion in epithelial ovarian cancer

机译：FOXM1的过表达预示不良预后并促进上皮性卵巢癌中癌细胞的增殖迁移和侵袭

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摘要

BackgroundThe Forkhead box M1 (FOXM1), an important regulator of cell differentiation and proliferation, is overexpressed in a number of aggressive human carcinomas. The purpose of this study was to examine the expression levels of FOXM1 in epithelial ovarian cancer (EOC), to identify the relationship between FOXM1 expression and patient survival, and to investigate the role of FOXM1 in human ovarian cancer development.

机译：背景叉头盒M1（FOXM1）是细胞分化和增殖的重要调节剂，在许多侵袭性人类癌症中过表达。这项研究的目的是检查上皮性卵巢癌（EOC）中FOXM1的表达水平，确定FOXM1表达与患者生存率之间的关系，并研究FOXM1在人类卵巢癌发展中的作用。

著录项

期刊名称 Journal of Translational Medicine
作者
Ning Wen; Yu Wang; Li Wen; Shu-Hua Zhao; Zhen-Hua Ai; Yi Wang; Bo Wu; Huai-Xiu Lu; Hong Yang; Wen-Chao Liu; Yu Li;
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作者单位

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年(卷),期 2014(12),-1
年度 2014
页码 134
总页数 13
原文格式 PDF
正文语种
中图分类医学史;
关键词
Ovarian cancer FOXM1 Prognosis Proliferation Migration Invasion;

机译：卵巢癌;FOXM1;预后;增殖;迁移;侵袭;

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专利

1. Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation, migration and invasion in epithelial ovarian cancer [J] . Ning Wen, Yu Wang, Li Wen, Journal of Translational Medicine . 2014,第1期

机译：FOXM1的过表达预示不良预后并促进上皮性卵巢癌中癌细胞的增殖，迁移和侵袭
2. Overexpression of G2 and S phase-expressed-1 contributes to cell proliferation, migration, and invasion via regulating p53/FoxM1/CCNB1 pathway and predicts poor prognosis in bladder cancer [J] . Liu Anwei, Zeng Shuxiong, Lu Xin, International Journal of Biological Macromolecules: Structure, Function and Interactions . 2019,第期

机译：通过调节P53 / FOXM1 / CCNB1途径，G2和S相表达-1的过表达有助于细胞增殖，迁移和侵袭，并预测膀胱癌的预后差
3. Overexpression of LAMC2 predicts poor prognosis in colorectal cancer patients and promotes cancer cell proliferation, migration, and invasion [J] . Dandan Huang, Changzheng Du, Dengbo Ji, Tumour biology : . 2017,第6期

机译：LAMC2的过表达预测结直肠癌患者的预后不良，并促进癌细胞的增殖，迁移和侵袭
4. Expression of Transcription Factor EB (TFEB) Promotes Cancer Cell Proliferation, Migration and Invasion [C] . Wei Li, Yang Liu, Min Hao, International conference on applied biotechnology . 2018

机译：转录因子EB（TFEB）的表达促进癌细胞的增殖，迁移和侵袭
5. Cadherin-11mediation of tumor progression and invasion in poor prognosis cancers: A viable therapeutic target. [D] . Guidry Auvil, Jaime Marie. 2009

机译：在不良预后的癌症中，Cadherin-11介导的肿瘤进展和侵袭：可行的治疗靶点。
6. Overexpression of TROP2 Predicts Poor Prognosis of Patients with Cervical Cancer and Promotes the Proliferation and Invasion of Cervical Cancer Cells by Regulating ERK Signaling Pathway [O] . Ting Liu, Yueyang Liu, Xiangxiang Bao, -1

机译：TROP2的过表达预测宫颈癌患者的预后差并通过调节ERK信号通路促进宫颈癌细胞的增殖和侵袭。
7. Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation, migration and invasion in epithelial ovarian cancer [O] . Ning Wen, Yu Wang, Li Wen, 2014

机译：FOXM1的过表达预示不良预后并促进上皮性卵巢癌中癌细胞的增殖，迁移和侵袭

Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation migration and invasion in epithelial ovarian cancer

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