首页> 外国专利> DIAGNOSTIC KIT FOR PREDICTING THE PROGNOSIS OF INVASIVE OR NON-MUSCLE INVASIVE BLADDER CANCER, METHOD FOR PREDICTING THE PROGNOSIS OF BLADDER CANCER, AND BLADDER CANCER MEDICINE SCREENING METHOD

DIAGNOSTIC KIT FOR PREDICTING THE PROGNOSIS OF INVASIVE OR NON-MUSCLE INVASIVE BLADDER CANCER, METHOD FOR PREDICTING THE PROGNOSIS OF BLADDER CANCER, AND BLADDER CANCER MEDICINE SCREENING METHOD

机译:用于预测侵袭性或非肌肉侵袭性膀胱癌的预后的诊断工具,预测膀胱癌的预后的方法以及膀胱癌的药物检查方法

摘要

The present invention relates to a diagnostic kit for predicting the prognosis of invasive or non-muscle invasive bladder cancer, to a method for predicting the prognosis of bladder cancer, and to a bladder cancer medicine screening method. More particularly, the present invention relates to a diagnostic kit for predicting the prognosis of bladder cancer, comprising, as active ingredients, primer pairs, a probe, or an antibody for a gene-classifier which statistically analyzes gene expression among normal tissues and bladder cancer tissues by using a micro-array to predict the reoccurrence or progression of non-muscle invasive bladder cancer, or for a gene-classifier which may predict the progression of invasive bladder cancer, cancer-specific survival, or total survival. The present invention also relates to a method for predicting the prognosis of bladder cancer using the primer pairs, the probe, or the antibody. The method of the present invention predicts the prognosis of bladder cancer in an inexpensive, convenient, and quick manner, and is useful in screening bladder cancer medicine.
机译:本发明涉及一种用于预测浸润性或非肌肉浸润性膀胱癌的预后的诊断试剂盒,一种用于预测膀胱癌的预后的方法,以及一种用于膀胱癌的药物筛选方法。更具体地,本发明涉及用于预测膀胱癌的预后的诊断试剂盒,其包含作为引物对,用于基因分类器的探针或抗体作为活性成分,所述统计学分类器统计地分析正常组织和膀胱癌之间的基因表达。通过使用微阵列预测非肌肉浸润性膀胱癌的复发或进展,或针对可预测浸润性膀胱癌的进展,癌症特异性生存或总生存的基因分类器,组织。本发明还涉及使用引物对,探针或抗体来预测膀胱癌的预后的方法。本发明的方法以廉价,方便和快速的方式预测膀胱癌的预后,并且可用于筛选膀胱癌药物。

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