Cytotoxic and inflammatory potential of a phospholipase A2 from Bothrops jararaca snake venom

机译：两种蛇毒蛇毒磷脂酶A2的细胞毒性和炎性潜能

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摘要

BackgroundSnake venom phospholipases A2 (PLA2s) have been reported to induce myotoxic, neurotoxic, hemolytic, edematogenic, cytotoxic and proinflammatory effects. This work aimed at the isolation and functional characterization of a PLA2 isolated from Bothrops jararaca venom, named BJ-PLA2-I.

机译：背景技术据报道，蛇毒磷脂酶A2（PLA2s）可以诱导肌毒性，神经毒性，溶血性，水肿性，细胞毒性和促炎作用。这项工作的目的是分离并分离自命名为BJ-PLA2-I的两种植物（Bothrops jararaca毒液）的PLA2。

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期刊名称 The Journal of Venomous Animals and Toxins Including Tropical Diseases
作者
Rafhaella C. A. Cedro; Danilo L. Menaldo; Tássia R. Costa; Karina F. Zoccal; Marco A. Sartim; Norival A. Santos-Filho; Lúcia H. Faccioli; Suely V. Sampaio;
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作者单位

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年(卷),期 2018(24),-1
年度 2018
页码 33
总页数 14
原文格式 PDF
正文语种
中图分类毒物学（毒理学）;
关键词
Snake venom Bothrops jararaca Phospholipase A2 Inflammation Cytotoxicity;

机译：蛇毒;Both虫;植物磷脂酶A2;炎症;细胞毒性;
入库时间 2022-08-17 11:46:45

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1. 日本蝮蛇蛇毒磷脂酶A2(Gln49-PLA2)的细胞毒性 [J] . 荆晓艳, 杨巍, 包永明, 动物学报（英文版） . 2006,第003期
2. Cytotoxic and inflammatory potential of a phospholipase A2 from Bothrops jararaca snake venom [J] . Rafhaella C. A. Cedro, Danilo L. Menaldo, Tássia R. Costa, Journal of venomous animals and toxins . 2018,第2016期

机译：蛇麻草蛇毒中磷脂酶A2的细胞毒性和炎性潜能
3. Cytotoxic and inflammatory potential of a phospholipase ASubscript2/Subscript from Emphasis Type="Italic"Bothrops jararaca/Emphasis snake venom [J] . Rafhaella C. A. Cedro, Danilo L. Menaldo, T??ssia R. Costa, Journal of Venomous Animals and Toxins including Tropical Diseases . 2018,第1期

机译： Bothrops jararaca 蛇毒中磷脂酶A 2 的细胞毒性和炎性潜能
4. A novel phospholipase A2, BJ-PLA2, from the venom of the snake Bothrops jararaca: purification, primary structure analysis, and its characterization as a platelet-aggregation-inhibiting factor. [J] . Serrano SM, Mentele R, Auerswald EA, Archives of Biochemistry and Biophysics . 1999,第1期

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5. Potent and selective 2-oxoamide inhibitors of phospholipases A2 as novel medicinal agents for the treatment of inflammatory diseases [C] . Efrosini Barbayianni, Georgia Antonopoulou, George Kokotos IUPAC World Congress on Chemistry . 2015

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6. VENOM COAGGLUTININ (VCA). THE PLATELET AGGREGATING PRINCIPLE OF BOTHROPS VENOMS: VON WILLEBRAND FACTOR-DEPENDENT PLATELET AGGREGATION. [D] . READ, MARJORIE SHEARIN. 1983

机译：蛇毒凝集素（VCA）。蛇毒的血小板聚集原理：冯·威勒伯兰德依赖血小板的聚集。
7. Cytotoxic and pro-apoptotic action of MjTX-I a phospholipase A2 isolated from Bothrops moojeni snake venom towards leukemic cells [O] . Rogério Bodini Benati, Tássia Rafaela Costa, Maira da Costa Cacemiro, 2018

机译：MjTX-1（一种从Bothrops moojeni蛇毒中分离出的磷脂酶A2）对白血病细胞的细胞毒性和促凋亡作用
8. Cytotoxic and inflammatory potential of a phospholipase A2 from Bothrops jararaca snake venom [O] . Rafhaella C. A. Cedro, Danilo L. Menaldo, Tássia R. Costa, 2018

机译：Hothrops Jararaca蛇毒液的磷脂酶A2的细胞毒性和炎症潜力

Cytotoxic and inflammatory potential of a phospholipase A2 from Bothrops jararaca snake venom

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