首页> 美国卫生研究院文献>The Journal of Veterinary Medical Science >Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus)
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Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus)

机译:获救的普通棕榈麝香中帕拉西酮-美托咪定和瓦坦胺-左拉西p的比较

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摘要

Forty rescued common palm civets were anesthetized. Twenty animals received intramuscular injections of alfaxalone 5 mg/kg and medetomidine 0.05 mg/kg (A-M group), whereas twenty animals received 5 mg/kg of tiletamine and zolazepam (T-Z group). The A-M group was reversed with atipamazole 0.25 mg/kg. There were no significant differences in the time from anesthetic injection to induction and intubation between the A-M and T-Z groups. The time from the injection of reversal in the A-M group and the time from cessation of isoflurane in the T-Z group to extubation, first response to recovery and ambulation were longer (P<0.05) in the T-Z group. The T-Z group recorded lower (P<0.05) rectal temperatures compared to the A-M group. This study showed that both drug combinations can be used effectively for the immobilization of civets. The A-M combination provided better anesthetic depth, but with higher incidence of bradycardia and hypoxemia. The recovery time was reduced significantly as atipamezole was used as a reversal agent in the A-M combination.
机译:麻醉了40只获救的普通棕榈palm。二十只动物肌肉注射阿法沙酮5 mg / kg和美托咪定0.05 mg / kg(A-M组),而二十只动物接受5 mg / kg的瓦坦胺和左拉西p(T-Z组)。 A-M组用0.25 mg / kg阿替吡唑逆转。从麻醉剂注射到诱导和插管的时间在A-M和T-Z组之间没有显着差异。在A-M组中,从逆转注射开始的时间以及在T-Z组中,从异氟烷停止到拔管的时间,在T-Z组中,对恢复和移动的第一反应时间更长(P <0.05)。与A-M组相比,T-Z组的直肠温度更低(P <0.05)。这项研究表明,两种药物组合均可有效地用于固定花ive。 A-M组合可提供更好的麻醉深度,但心动过缓和低氧血症的发生率更高。由于在A-M组合中使用阿替哌唑作为逆转剂,因此恢复时间大大缩短。

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